Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a …

M Manns, P Marcellin, F Poordad, ESA De Araujo… - The Lancet, 2014 - thelancet.com
Background Pegylated interferon (peginterferon) alfa 2a or 2b plus ribavirin regimens were
the standard of care in patients with hepatitis C virus (HCV) infection, but the sustained …

Nanomedicines in the treatment of hepatitis C virus infection in Asian patients: optimizing use of peginterferon alfa

CH Liu, JH Kao - International journal of nanomedicine, 2014 - Taylor & Francis
Asia is endemic for hepatitis C virus (HCV) infection, which is the leading cause of cirrhosis,
hepatic decompensation, hepatocellular carcinoma, and liver transplantation worldwide …

Optimizing treatment for HCV genotype 4: PEG‐IFN alfa 2a vs. PEG‐IFN alfa 2b; the debate continues

G Esmat, M El Kassas, M Hassany, M Gamil… - Liver …, 2014 - Wiley Online Library
Hepatitis C virus (HCV) remains one of the leading causes of morbidity and mortality
worldwide. Combined therapy with pegylated interferon (PEG‐IFN) and ribavirin is the …

Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C

G Hauser, T Awad, J Brok, K Thorlund… - Cochrane database …, 2014 - cochranelibrary.com
Background Pegylated interferon (peginterferon) plus ribavirin is the recommended
treatment for patients with chronic hepatitis C, but systematic assessment of the effect of this …

Peginterferon alpha‐2a versus peginterferon alpha‐2b for chronic hepatitis C

G Hauser, T Awad, K Thorlund… - Cochrane Database …, 2014 - cochranelibrary.com
Background A combination of weekly pegylated interferon (peginterferon) alpha and daily
ribavirin still represents standard treatment of chronic hepatitis C infection in the majority of …

SVR12 is higher than SVR24 in treatment-naive hepatitis C genotype 1 patients treated with peginterferon plus ribavirin

K Thorlund, E Druyts, EJ Mills - Clinical Epidemiology, 2014 - Taylor & Francis
Background Randomized clinical trials (RCTs) of interventions for the hepatitis C virus have
historically used sustained virological response (SVR) at 24 weeks after treatment (SVR24) …

The clinical effectiveness and cost-effectiveness of peginterferon alfa and ribavirin for the treatment of chronic hepatitis C in children and young people: a systematic …

D Hartwell, K Cooper, GK Frampton… - Health Technology …, 2014 - researchportal.port.ac.uk
Background Optimal therapy for children with chronic hepatitis C is unclear. Two treatment
regimens are currently licensed in children. Objectives To assess the clinical effectiveness …

Comparison of peginterferon alfa-2a and alfa-2b for treatment of patients with chronic hepatitis C: a retrospective study using the Japanese Interferon Database

I Sato, T Shimbo, Y Kawasaki… - Drug design, development …, 2014 - Taylor & Francis
Purpose We aimed to compare the rates of sustained virologic response (SVR) achieved
with peginterferon (PEG-IFN) alfa-2a and alfa-2b in combination with ribavinin (RBV) for …

Гепатит С вирусная инфекция (диагностика, структура клинических проявлений и исходов, молекулярно-генетические и иммунные механизмы патогенеза …

В монографии на основе анализа данных современной литературы и результатов
собственной работы обсуждаются различные аспекты эпидемиологии, патогенеза …

[HTML][HTML] Chronic hepatitis C genotype 1 virus: who should wait for treatment?

CV Tovo, AA de Mattos… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Elucidation of the natural history of chronic hepatitis C (CHC) and the identification of risk
factors for its progression to advanced liver disease have allowed many physicians to …