Single nucleotide polymorphism genotyping using Kompetitive Allele Specific PCR (KASP): overview of the technology and its application in crop improvement

K Semagn, R Babu, S Hearne, M Olsen - Molecular breeding, 2014 - Springer
Single nucleotide polymorphism (SNP) data can be obtained using one of the numerous
uniplex or multiplex SNP genotyping platforms that combine a variety of chemistries …

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

TFC Mackay - Nature Reviews Genetics, 2014 - nature.com
The role of epistasis in the genetic architecture of quantitative traits is controversial, despite
the biological plausibility that nonlinear molecular interactions underpin the genotype …

Natural variations and genome-wide association studies in crop plants

X Huang, B Han - Annual review of plant biology, 2014 - annualreviews.org
Natural variants of crops are generated from wild progenitor plants under both natural and
human selection. Diverse crops that are able to adapt to various environmental conditions …

Insights into the maize pan-genome and pan-transcriptome

CN Hirsch, JM Foerster, JM Johnson, RS Sekhon… - The Plant …, 2014 - academic.oup.com
Genomes at the species level are dynamic, with genes present in every individual (core) and
genes in a subset of individuals (dispensable) that collectively constitute the pan-genome …

Detecting epistasis in human complex traits

WH Wei, G Hemani, CS Haley - Nature Reviews Genetics, 2014 - nature.com
Genome-wide association studies (GWASs) have become the focus of the statistical analysis
of complex traits in humans, successfully shedding light on several aspects of genetic …

The genetic architecture of maize height

JA Peiffer, MC Romay, MA Gore, SA Flint-Garcia… - Genetics, 2014 - academic.oup.com
Height is one of the most heritable and easily measured traits in maize (Zea mays L.). Given
a pedigree or estimates of the genomic identity-by-state among related plants, height is also …

[HTML][HTML] Genome wide association studies using a new nonparametric model reveal the genetic architecture of 17 agronomic traits in an enlarged maize association …

N Yang, Y Lu, X Yang, J Huang, Y Zhou, F Ali… - PLoS …, 2014 - journals.plos.org
Association mapping is a powerful approach for dissecting the genetic architecture of
complex quantitative traits using high-density SNP markers in maize. Here, we expanded …

Back to the wilds: tapping evolutionary adaptations for resilient crops through systematic hybridization with crop wild relatives

E Warschefsky, RV Penmetsa, DR Cook… - American journal of …, 2014 - Wiley Online Library
The genetic diversity of our crop plants has been substantially reduced during the process of
domestication and breeding. This reduction in diversity necessarily constrains our ability to …

[HTML][HTML] A SUPER powerful method for genome wide association study

Q Wang, F Tian, Y Pan, ES Buckler, Z Zhang - PloS one, 2014 - journals.plos.org
Genome-Wide Association Studies shed light on the identification of genes underlying
human diseases and agriculturally important traits. This potential has been shadowed by …

Novel methods to optimize genotypic imputation for low‐coverage, next‐generation sequence data in crop plants

K Swarts, H Li, JA Romero Navarro, D An… - The Plant …, 2014 - Wiley Online Library
Next‐generation sequencing technology such as genotyping‐by‐sequencing (GBS) made
low‐cost, but often low‐coverage, whole‐genome sequencing widely available. Extensive …