Novel approaches in polyepitope T-cell vaccine development against HIV-1
LI Karpenko, SI Bazhan, DV Antonets… - Expert review of …, 2014 - Taylor & Francis
RV144 clinical trial was modestly effective in preventing HIV infection. New alternative
approaches are needed to design improved HIV-1 vaccines and their delivery strategies …
approaches are needed to design improved HIV-1 vaccines and their delivery strategies …
Episomal Expression of Truncated Listeriolysin O in LmddA-LLO–E7 Vaccine Enhances Antitumor Efficacy by Preferentially Inducing Expansions of CD4+ FoxP3− and …
Z Chen, L Ozbun, N Chong, A Wallecha… - Cancer immunology …, 2014 - AACR
Studies have shown that Listeria monocytogenes (Lm)–based vaccine expressing a fusion
protein comprising truncated listeriolysin O (LLO) and human papilloma virus (HPV) E7 …
protein comprising truncated listeriolysin O (LLO) and human papilloma virus (HPV) E7 …
Heteroclitic analogs and related methods
S Tangri, A Sette, G Ishioka, JD Fikes - US Patent 8,741,576, 2014 - Google Patents
Heteroclitic analogs of Class I epitopes are prepared by providing conservative or semi-
conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes. The …
conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes. The …
Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8+ T Cell Epitopes
S Rotem, O Cohen, E Bar-Haim, L Bar-On, S Ehrlich… - PLoS …, 2014 - journals.plos.org
Recently we described an unbiased bacterial whole-genome immunoinformatic analysis
aimed at selection of potential CTL epitopes located in “hotspots” of predicted MHC-I …
aimed at selection of potential CTL epitopes located in “hotspots” of predicted MHC-I …