Obesity and neuroinflammation: a pathway to cognitive impairment
AA Miller, SJ Spencer - Brain, behavior, and immunity, 2014 - Elsevier
Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …
including cognitive dysfunction. In this review we will address the evidence that obesity and …
Environment and brain plasticity: towards an endogenous pharmacotherapy
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …
structure and function in response to experience, a fundamental theoretical theme in the …
Stress, glucocorticoid receptors, and adult neurogenesis: a balance between excitation and inhibition?
DJ Saaltink, E Vreugdenhil - Cellular and Molecular Life Sciences, 2014 - Springer
Adult neurogenesis, the birth of new neurons in the mature brain, has attracted considerable
attention in the last decade. One of the earliest identified and most profound factors that …
attention in the last decade. One of the earliest identified and most profound factors that …
Changes in mitochondrial function are pivotal in neurodegenerative and psychiatric disorders: how important is BDNF?
A Markham, R Bains, P Franklin… - British journal of …, 2014 - Wiley Online Library
The brain is at the very limit of its energy supply and has evolved specific means of adapting
function to energy supply, of which mitochondria form a crucial link. Neurotrophic and …
function to energy supply, of which mitochondria form a crucial link. Neurotrophic and …
Voluntary wheel running, but not a diet containing (−)-epigallocatechin-3-gallate and β-alanine, improves learning, memory and hippocampal neurogenesis in aged …
TE Gibbons, BD Pence, G Petr, JM Ossyra… - Behavioural brain …, 2014 - Elsevier
Aging is associated with impaired learning and memory accompanied by reductions in adult
hippocampal neurogenesis and brain expression of neurotrophic factors among other …
hippocampal neurogenesis and brain expression of neurotrophic factors among other …
The impact of surgery and anesthesia on post-operative cognitive decline and Alzheimer's disease development: biomarkers and preventive strategies
AK Kapila, HR Watts, T Wang… - Journal of Alzheimer's …, 2014 - content.iospress.com
Alzheimer's disease (AD) is a major social and clinical burden in the elderly, affecting 5% of
people aged over 65 and 20% aged over 80. Despite improved management, a cure has not …
people aged over 65 and 20% aged over 80. Despite improved management, a cure has not …
Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of …
KJ Speaker, SS Cox, MM Paton, A Serebrakian… - Brain, behavior, and …, 2014 - Elsevier
To prime local tissues for dealing with potential infection or injury, exposure to an acute,
intense stressor evokes increases in circulating and local tissue inflammatory proteins …
intense stressor evokes increases in circulating and local tissue inflammatory proteins …
Differential cortical neurotrophin and cytogenetic adaptation after voluntary exercise in normal and amnestic rats
Voluntary exercise (VEx) has profound effects on neural and behavioral plasticity, including
recovery of CNS trauma and disease. However, the unique regional cortical adaption to VEx …
recovery of CNS trauma and disease. However, the unique regional cortical adaption to VEx …
Swimming improves the emotional memory deficit by scopolamine via mu opioid receptors
Aims The aim of the present study was to investigate the effect of swimming exercise on
elevated plus-maze (EPM)-associated memory deficit induced by intra-CA1 injection of …
elevated plus-maze (EPM)-associated memory deficit induced by intra-CA1 injection of …
Low-grade inflammation disrupts structural plasticity in the human brain
C Szabó, O Kelemen, S Kéri - Neuroscience, 2014 - Elsevier
Increased low-grade inflammation is thought to be associated with several neuropsychiatric
disorders characterized by decreased neuronal plasticity. The purpose of the present study …
disorders characterized by decreased neuronal plasticity. The purpose of the present study …