Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

J Ryynänen, A Neme, TP Tuomainen… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Vitamin D3, its biologically most active metabolite 1α, 25‐dihydroxyvitamin D3 (1, 25
(OH) 2D3), and the vitamin D receptor (VDR) are important for adipose tissue biology …

Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance

ML Goodson, BM Young, CA Snyder… - … and cellular biology, 2014 - Am Soc Microbiol
Alternative mRNA splicing is an important means of diversifying function in higher
eukaryotes. Notably, both NCoR and SMRT corepressors are subject to alternative mRNA …

[PDF][PDF] Pleiotropy of vitamin D-mediated gene regulation

J Ryynänen - 2014 - erepo.uef.fi
ABSTRACT The steroid hormone 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) is the active
metabolite of vitamin D3 that regulates the transcription of hundreds of primary target genes …