[PDF][PDF] Indices to assess patients with systemic lupus erythematosus in clinical trials, long-term observational studies, and clinical care

I Castrejón, C Tani, M Jolly, A Huang… - Clin Exp …, 2014 - clinexprheumatol.org
This review summarises most currently used indices to assess and monitor patients with
systemic lupus erythematosus (SLE) in clinical trials, long-term observational studies, and …

Outcome measures for primary Sjögren's syndrome: a comprehensive review

R Seror, E Theander, H Bootsma, SJ Bowman… - Journal of …, 2014 - Elsevier
Lymphocytic infiltration of different exocrine and non-exocrine epithelia is the pathological
hallmark of primary Sjögren's syndrome, whereas involvement of salivary and lachrymal …

[PDF][PDF] Efficacy and safety of abatacept in lupus nephritis: a twelve‐month, randomized, double‐blind study

R Furie, K Nicholls, TT Cheng, F Houssiau… - Arthritis & …, 2014 - Wiley Online Library
Objective To compare the efficacy and safety of intravenous (IV) abatacept, a selective T cell
costimulation modulator, versus placebo for the treatment of active class III or IV lupus …

Systemic symptoms in the progression of cutaneous to systemic lupus erythematosus

IT Wieczorek, KJ Propert, J Okawa… - JAMA dermatology, 2014 - jamanetwork.com
Importance Patients with cutaneous lupus erythematosus (CLE) who develop systemic lupus
erythematosus (SLE) may have few and mild systemic symptoms. Objective To characterize …

Suppression of inflammation reduces endothelial microparticles in active systemic lupus erythematosus

B Parker, A Al-Husain, P Pemberton… - Annals of the …, 2014 - ard.bmj.com
Background In a prospective observational study, we investigated whether patients with
active systemic lupus erythematosus (SLE) had higher indices of endothelial damage and …

Associations of clinical features and prognosis with age at disease onset in patients with systemic lupus erythematosus

X Feng, Y Zou, W Pan, X Wang, M Wu, M Zhang… - Lupus, 2014 - journals.sagepub.com
The objective of this study is to evaluate the association of clinical features and prognosis
with age at disease onset in patients with systemic lupus erythematosus (SLE) in a large …

Treatment of moderately to severely active systemic lupus erythematosus with adrenocorticotropic hormone: a single-site, open-label trial

JJ Fiechtner, T Montroy - Lupus, 2014 - journals.sagepub.com
Background Alternative therapeutic options are needed for patients with systemic lupus
erythematosus (SLE) not adequately controlled with or intolerant to traditional treatments …

A surge in anti-dsDNA titer predicts a severe lupus flare within six months

N Pan, I Amigues, S Lyman, R Duculan, F Aziz… - Lupus, 2014 - journals.sagepub.com
Objective Rising anti-double-stranded (ds) DNA titers have been shown by some, but not all,
studies to be predictive of disease flares in systemic lupus erythematosus (SLE). We …

Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the …

IEM Bultink, NC Harvey, A Lalmohamed… - Osteoporosis …, 2014 - Springer
The incidence of clinical fractures and the associated factors were assessed in patients with
systemic lupus erythematosus (SLE) versus matched controls. We found an increased …

Mucocutaneous manifestations in a UK national cohort of juvenile-onset systemic lupus erythematosus patients

D Chiewchengchol, R Murphy, T Morgan… - …, 2014 - academic.oup.com
Objective. To determine whether mucocutaneous manifestations are associated with major
organ involvement in a UK national cohort of juvenile-onset SLE (JSLE) patients. Methods …