Monocytes as regulators of inflammation and HIV‐related comorbidities during cART

JJ Anzinger, TR Butterfield… - Journal of …, 2014 - Wiley Online Library
Combined antiretroviral therapy (cART) extends the lifespan and the quality of life for HIV‐
infected persons but does not completely eliminate chronic immune activation and …

Incorporating biomarkers into cancer and aging research

JM Hubbard, HJ Cohen, HB Muss - Journal of Clinical Oncology, 2014 - ascopubs.org
The challenge in treating the older adult with cancer is accurately accounting for and
adapting management to the heterogeneity in health status of the individual patient. Many …

[HTML][HTML] Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity

O Addison, MJ Drummond, PC LaStayo… - The Journal of nutrition …, 2014 - Elsevier
Objectives Intramuscular adipose tissue (IMAT) is recognized as a negative predictor of both
muscle and mobility function in older adults, however the mechanism by which IMAT may …

Extracts of Cistanche deserticola Can Antagonize Immunosenescence and Extend Life Span in Senescence‐Accelerated Mouse Prone 8 (SAM‐P8) Mice

K Zhang, X Ma, W He, H Li, S Han… - Evidence‐Based …, 2014 - Wiley Online Library
The senescence accelerated mouse prone 8 substrain (SAM‐P8), widely accepted as an
animal model for studying aging and antiaging drugs, was used to examine the effects of …

[HTML][HTML] Combined influence of dietary restriction and treadmill running on MCP-1 and the expression of oxidative stress-related mRNA in the adipose tissue in obese …

N Ahn, K Kim - Journal of Exercise Nutrition & Biochemistry, 2014 - ncbi.nlm.nih.gov
[Purpose] This study suggests that the negative effects of inflammation caused by obesity
could be prevented through diet restriction and exercise.[Methods] In this study, 44 C57/BL6 …

Diagnostic methods and biomarkers for Alzheimer's disease

E Bagyinszky, YC Youn, SSA An, SY Kim - Toxicology and Environmental …, 2014 - Springer
Alzheimer's disease (AD) is the most frequently occurring and intensively investigated
neurodegenerative disorder, which is associated with extracellular senile plaques and …

Advanced age of renal transplant recipients correlates with increased plasma concentrations of interleukin-6, chemokine ligand 2 (CCL2), and matrix …

O Mazanowska, M Żabińska… - Transplantation …, 2014 - Elsevier
Background Advanced age of renal transplant recipients (RTRs) has a negative impact on
kidney allograft survival through impaired extracellular matrix degradation by the matrix …

The effects of menopause on autoimmune diseases

MA Farage, KW Miller, HI Maibach - Skin, mucosa and menopause …, 2014 - Springer
Despite the fact that women living in industrialized countries are likely to spend one-third of
their lives in menopause, the influence of the estrogen withdrawal associated with …

There are no differences in IL-6, CRP and homocystein concentrations between women whose mothers had AD and women whose mothers did not have AD

S Devčić, L Glamuzina, N Ruljancic, M Mihanovic - Psychiatry research, 2014 - Elsevier
A wide range of recent studies have detected inflammation as one of the most influent
factors in the appearance and spreading of neurodegenerative brain diseases. We aimed to …

Genes, Hormones, Immunosenescence, and Environmental Agents: Toward an Integrated View of the Genesis of Autoimmune Disease

MA Farage, KW Miller, RG Lahita - Skin, Mucosa and Menopause …, 2014 - Springer
Autoimmune diseases, a group of dozens of distinct disorders that target every organ
system, affect as much as 10% of the US population and are increasing in prevalence …