Purpose Treatment with statins requires close monitoring of serum creatine kinase (CK)
levels to prevent myopathy, a common and potentially serious dose-dependent adverse …

Genetic variation in the multidrug resistance gene ABCB1, which encodes the efflux
transporter P-glycoprotein (P-gp), has been associated with Parkinson disease. Our goal …

В обзоре литературы охарактеризована структура и функции гликопротеина Р,
описаны особенности его субстратов, индукторов и ингибиторов и возможности …

In the review of literature, the structure and functions of P-glycoprotein are characterized,
features of its substrates, inductors and inhibitors and possibility of forecasting of belonging …

Reflecting the interdisciplinary nature of biotechnology, this book covers the role of targeted
delivery of polymeric nanodrugs to cancer cells, microbial detoxifying enzymes in …

Les immunosuppresseurs sont des médicaments ayant démontré leur efficacité dans la
prévention du rejet de transplantation d'organe solide. Néanmoins, ces médicaments …

Cilengitide is an αvβ3/αvβ5‐integrin inhibitor investigated as an anticancer agent. This study
aimed to develop a cilengitide population pharmacokinetic model using nonlinear mixed …

Magnitude of the information regarding pharmacogenetics and pharmacogenomics with
increasing knowledge in the field of molecular biology has profoundly augmented day-by …

P-glycoprotein (P-gp), encoded by ABCB1 genes, is a membrane efflux transporter normally
expressed in human tissues such as the small intestine, the biliary canalicular front of …

__Abstract__ When an individual's kidneys fail, there are three treatment options:
hemodialysis, peritoneal dialysis or kidney transplantation. A successful kidney …