Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: synthesis, cytotoxic activity and molecular modeling
Novel pyrrole and pyrrolopyrimidine scaffold-based sulfonamides were designed and
synthesized. The carbonic anhydrase (CA) inhibition ability of all derivatives was assessed …
synthesized. The carbonic anhydrase (CA) inhibition ability of all derivatives was assessed …
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
A Arasappan, FG Njoroge, CD Kwong… - US Patent …, 2014 - Google Patents
2009-11-05 Assigned to SOUTHERN RESEARCH INSTITUTE reassignment SOUTHERN
RESEARCH INSTITUTE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
RESEARCH INSTITUTE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
CD Kwong, FG Njoroge, S Ananthan, J Clark… - US Patent …, 2014 - Google Patents
R22, R23, and n is selected independently and as de? ned (65) Prior Publication Data
herein. Compositions comprising such compounds are also provided. The compounds of the …
herein. Compositions comprising such compounds are also provided. The compounds of the …
Aurora 激酶及其抑制剂的研究进展
朱海静， 焦宇 - 中国现代应用药学, 2014 - cqvip.com
目的从结构出发介绍Aurora 激酶及其抑制剂的研究进展. 方法总结Aurora
激酶抑制剂骨架特征和结合模式, 以及进入临床的Aurora 激酶抑制剂的研究进展 …
激酶抑制剂骨架特征和结合模式, 以及进入临床的Aurora 激酶抑制剂的研究进展 …
[HTML][HTML] Molecular docking of 1H-pyrazole derivatives to receptor tyrosine kinase and protein kinase for screening potential inhibitors
VG Javaregowda, BH Doreswamy, S Ningaiah… - …, 2014 - ncbi.nlm.nih.gov
Tyrosine kinase receptor and protein kinases drawn much attention for the scientific
fraternity in drug discovery due to its important role in different cancer, cardiovascular …
fraternity in drug discovery due to its important role in different cancer, cardiovascular …
1‑calcium phosphate‑uracil, a synthesized pyrimidine derivative agent, has anti‑proliferative, pro‑apoptotic and anti‑invasion effects on multiple tumor cell lines
J Peng, X Chen, Q Hu, M Yang… - Molecular …, 2014 - spandidos-publications.com
1-calcium phosphate-uracil (1-CP-U), a synthetic pyrimidine derivative, has been
documented to demonstrate a variety of different biological activities. However, the potency …
documented to demonstrate a variety of different biological activities. However, the potency …