[HTML][HTML] Virology and cell biology of the hepatitis C virus life cycle–An update
J Dubuisson, FL Cosset - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
Virus-host interactomics: new insights and opportunities for antiviral drug discovery
B De Chassey, L Meyniel-Schicklin, J Vonderscher… - Genome medicine, 2014 - Springer
The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
The intrinsic disorder status of the human hepatitis C virus proteome
Many viral proteins or their biologically important regions are disordered as a whole, or
contain long disordered regions. These intrinsically disordered proteins/regions do not …
contain long disordered regions. These intrinsically disordered proteins/regions do not …
Functional characterization of nuclear localization and export signals in hepatitis C virus proteins and their role in the membranous web
A Levin, CJ Neufeldt, D Pang, K Wilson… - PloS one, 2014 - journals.plos.org
The hepatitis C virus (HCV) is a positive strand RNA virus of the Flavivirus family that
replicates in the cytoplasm of infected hepatocytes. Previously, several nuclear localization …
replicates in the cytoplasm of infected hepatocytes. Previously, several nuclear localization …
Asunaprevir, a protease inhibitor for the treatment of hepatitis C infection
I Gentile, AR Buonomo, E Zappulo, G Minei… - … and clinical risk …, 2014 - Taylor & Francis
According to the World Health Organization, approximately 150 million people worldwide
are chronic carriers of hepatitis C virus (HCV). HCV infection can evolve into cirrhosis of the …
are chronic carriers of hepatitis C virus (HCV). HCV infection can evolve into cirrhosis of the …
ABT-450: a novel protease inhibitor for the treatment of hepatitis C virus infection
I Gentile, F Borgia, A Riccardo Buonomo… - Current medicinal …, 2014 - ingentaconnect.com
About 2.3% of the world's population is infected with hepatitis C virus (HCV) and patients
have a high risk of developing liver cirrhosis and its complications. Current therapeutic …
have a high risk of developing liver cirrhosis and its complications. Current therapeutic …
Mass spectrometry-based proteomic approaches for discovery of HIV–host interactions
Y Luo, MA Muesing - Future virology, 2014 - Taylor & Francis
ABSTRACT A molecular understanding of viral infection requires a multi-disciplinary
approach. Mass spectrometry has emerged as an indispensable tool to investigate the …
approach. Mass spectrometry has emerged as an indispensable tool to investigate the …
[HTML][HTML] The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production
CA Eberle, M Zayas, A Stukalov, A Pichlmair, G Alvisi… - Virology, 2014 - Elsevier
Hepatitis C virus (HCV) is a considerable global health and economic burden. The HCV
nonstructural protein (NS) 5A is essential for the viral life cycle. The ability of NS5A to …
nonstructural protein (NS) 5A is essential for the viral life cycle. The ability of NS5A to …
Virus-host interactomics: new insights and opportunities for antiviral drug discovery
L Meyniel-Schicklin, J Vonderscher, P Andrn… - Genome …, 2014 - go.gale.com
The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
Étude de la duplication du domaine V3 de la région NS5A du Virus de l'Hépatite C de génotype 1b: Épidémiologie clinique et moléculaire et aspects fonctionnels
H Le Guillou-Guillemette - 2014 - theses.hal.science
L'infection par le virus de l'hépatite C (VHC) est responsable d'hépatite chronique, de
cirrhose et de carcinome hépatocellulaire. La protéine NS5A du VHC participe à la …
cirrhose et de carcinome hépatocellulaire. La protéine NS5A du VHC participe à la …