Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Over the last decade, the active role of the microenvironment in the pathogenesis of B cell
lymphomas has been recognized, delivering signals that favor clonal expansion and drug …

Tissue-resident macrophages are highly heterogeneous in terms of their functions and
phenotypes as a consequence of adaptation to different tissue environments. Local tissue …

Prosenescence therapy has recently emerged as a novel therapeutic approach for treating
cancer. However, this concept is challenged by conflicting evidence showing that the …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Pneumonia is a major cause of mortality worldwide and a serious problem in critical care
medicine, but the immunophysiological processes that confer either protection or morbidity …

Mucosal surfaces are constantly exposed to environmental antigens, colonized by
commensal organisms and used by pathogens as points of entry. As a result, the immune …

Objective To identify a biomarker distinguishing patients who, despite a primary progressive
multiple sclerosis (PPMS) clinical course, may nonetheless benefit from immune therapy …

Abstract Titanium dioxide nanoparticles (TiO 2 NPs) have been widely used in various
areas, and its potential toxicity has gained wide attention. However, the molecular …

Resolution of inflammation is critical to restoration of tissue function after an inflammatory
response. We previously demonstrated that 12/15-lipoxygenase (12/15-LOX)-expressing …