Cellular processes are typically carried out by protein complexes and functional modules.
Identifying them plays an important role for our attempt to reveal principles of cellular …

The pace, by which scientific knowledge is being produced and shared today, was never
been so fast in the past. Different areas of science are getting closer to each other to give …

Many vaccines induce protective immunity via antibodies. Systems biology approaches
have been used to determine signatures that can be used to predict vaccine-induced …

SUMOylation is a reversible post-translational modification essential for genome stability.
Using high-resolution MS, we have studied global SUMOylation in human cells in a site …

Cytoscape is one of the most popular open‐source software tools for the visual exploration
of biomedical networks composed of protein, gene, and other types of interactions. It offers …

Biological network analysis is a powerful approach to gain systems-level understanding of
patterns of gene expression in different cell types, disease states and other biological …

Networks and network analysis are arguably one of the largest growth areas of the early
twenty-first century in the quantitative sciences. Despite roots in social network analysis …

Co-occurrence patterns are used in ecology to explore interactions between organisms and
environmental effects on coexistence within biological communities. Analysis of co …

Stem cells are highly abundant during early development but become a rare population in
most adult organs. The molecular mechanisms causing stem cells to exit proliferation at a …

By determining protein-protein interactions in normal, diseased and infected cells, we can
improve our understanding of cellular systems and their reaction to various perturbations. In …