Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
CM Theriot, MJ Koenigsknecht, PE Carlson Jr… - Nature …, 2014 - nature.com
Antibiotics can have significant and long-lasting effects on the gastrointestinal tract
microbiota, reducing colonization resistance against pathogens including Clostridium …
microbiota, reducing colonization resistance against pathogens including Clostridium …
Metabolic Fingerprint of Dimethyl Sulfone (DMSO2) in Microbial–Mammalian Co-metabolism
X He, CM Slupsky - Journal of proteome research, 2014 - ACS Publications
There is growing awareness that intestinal microbiota alters the energy harvesting capacity
of the host and regulates metabolism. It has been postulated that intestinal microbiota are …
of the host and regulates metabolism. It has been postulated that intestinal microbiota are …
Decline in presumptively protective gut bacterial species and metabolites are paradoxically associated with disease improvement in pediatric Crohn's disease during …
K Gerasimidis, M Bertz, L Hanske… - Inflammatory bowel …, 2014 - academic.oup.com
Background The gut microbiota is implicated in the pathogenesis of Crohn's disease (CD).
Exclusive enteral nutrition (EEN) is a successful treatment, but its mode of action remains …
Exclusive enteral nutrition (EEN) is a successful treatment, but its mode of action remains …
Effects of wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal parameters in healthy preadolescent children
IEJA François, O Lescroart… - Journal of Pediatric …, 2014 - journals.lww.com
Objectives: We assessed whether wheat bran extract (WBE) containing arabinoxylan-
oligosaccharides (AXOS) elicited a prebiotic effect and modulated gastrointestinal (GI) …
oligosaccharides (AXOS) elicited a prebiotic effect and modulated gastrointestinal (GI) …
p-Cresol affects reactive oxygen species generation, cell cycle arrest, cytotoxicity and inflammation/atherosclerosis-related modulators production in endothelial cells …
MC Chang, HH Chang, CP Chan, SY Yeung… - PLoS …, 2014 - journals.plos.org
Aims Cresols are present in antiseptics, coal tar, some resins, pesticides, and industrial
solvents. Cresol intoxication leads to hepatic injury due to coagulopathy as well as …
solvents. Cresol intoxication leads to hepatic injury due to coagulopathy as well as …
Cardiovascular disease relates to intestinal uptake of p-cresol in patients with chronic kidney disease
R Poesen, L Viaene, K Verbeke, P Augustijns… - BMC nephrology, 2014 - Springer
Background Serum p-cresyl sulfate (PCS) associates with cardiovascular disease in patients
with chronic kidney disease. PCS concentrations are determined by intestinal uptake of p …
with chronic kidney disease. PCS concentrations are determined by intestinal uptake of p …
Modulation of amino acid metabolic signatures by supplemented isoenergetic diets differing in protein and cereal fiber content
JG Hattersley, AFH Pfeiffer, M Roden… - The Journal of …, 2014 - academic.oup.com
Context: Amino-acid (AA) metabolic signatures differ in insulin-resistant (IR) obese vs
normal-weight subjects, improve after weight loss, and seem to predict the risk of type 2 …
normal-weight subjects, improve after weight loss, and seem to predict the risk of type 2 …
Serum Concentrations of p-Cresyl Sulfate and Indoxyl Sulfate, But Not Inflammatory Markers, Increase in Incident Peritoneal Dialysis Patients in Parallel with Loss of …
L Viaene, BKI Meijers, B Bammens… - Peritoneal Dialysis …, 2014 - journals.sagepub.com
Background High serum concentrations of the protein-bound uremic retention solutes p-
cresyl sulfate (PCS) and indoxyl sulfate (IndS) and inflammation are associated with …
cresyl sulfate (PCS) and indoxyl sulfate (IndS) and inflammation are associated with …
Heritability and Clinical Determinants of Serum Indoxyl Sulfate and p-Cresyl Sulfate, Candidate Biomarkers of the Human Microbiome Enterotype
L Viaene, L Thijs, Y Jin, Y Liu, Y Gu, B Meijers, K Claes… - PloS one, 2014 - journals.plos.org
Background Indoxyl sulfate and p-cresyl sulfate are unique microbial co-metabolites. Both
co-metabolites have been involved in the pathogenesis of accelerated cardiovascular …
co-metabolites have been involved in the pathogenesis of accelerated cardiovascular …
Cytotoxic Effects of p-Cresol in Renal Epithelial Tubular Cells
A Brocca, GM Virzì, M De Cal, V Cantaluppi… - Blood purification, 2014 - karger.com
Background: The uremic syndrome is characterized by a deterioration of kidney function due
to the accumulation of uremic toxins. Currently, 100 different uremic toxins have been …
to the accumulation of uremic toxins. Currently, 100 different uremic toxins have been …