Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction and
bone resorption. The proinflammatory cytokine interleukin 17 (IL‐17), primarily produced by …

Introduction: Stromal cell-derived factor 1 (SDF-1) is a potent chemoattractant cytokine with
various biological functions such as stem cell mobilization, inflammatory cell infiltration and …

Inflammatory angiogenesis and vascular remodeling play key roles in the chronic
inflammatory skin disease psoriasis, but little is known about the molecular mediators of …

Objective Stromal cell–derived factor 1 (SDF‐1) is a chemokine that is involved in the bone‐
destructive process in rheumatoid arthritis (RA) and bony metastasis in malignancy. This …

Hyaluronan (HA) may have proinflammatory roles in the context of CNS autoimmunity. It
accumulates in demyelinated multiple sclerosis (MS) lesions, promotes antigen …

Rhizoma Dioscoreae Nipponicae (RDN) is a widely used traditional Chinese herb, which is
used to treat arthroncus, arthrodynia and arthritis. As is known to us, inflammatory …

Based on these findings, blocking CXCR4 seems to be a therapeutic strategy in
inflammatory diseases. Several promising CXCR4 antagonists are in different stages of …

The CXCL12–CXCR4 axis is postulated to be a key pathway in the interaction between
(cancer) stem cells and their surrounding supportive cells in the (cancer) stem cell niche. As …

Systemic reactions to Hymenoptera stings can be fatal and represent a reduction in the
quality of life. The immune mechanisms involved in venom allergic subjects are barely …

The discovery that chemokines and their receptors are expressed by a variety of cell types
within the normal adult central nervous system (CNS) has led to an expansion of their …