The metabolic response to stress is part of the adaptive response to survive critical illness.
Several mechanisms are well preserved during evolution, including the stimulation of the …

Background Critical illness polyneuropathy or myopathy (CIP/CIM) is a frequent
complication in the intensive care unit (ICU) and is associated with prolonged mechanical …

Objective: Survivors of severe critical illness frequently develop substantial and persistent
physical complications, including muscle weakness, impaired physical function, and …

Rationale: Intensive care unit (ICU)-acquired weakness is a frequent complication of critical
illness. It is unclear whether it is a marker or mediator of poor outcomes. Objectives: To …

Rationale: Profound muscle weakness during and after critical illness is termed intensive
care unit–acquired weakness (ICUAW). Objectives: To develop diagnostic …

Background: Increasing numbers of survivors of critical illness are at risk for physical,
cognitive, and/or mental health impairments that may persist for months or years after …

Rationale: Existing studies of risk factors for physical impairments in acute lung injury (ALI)
survivors were potentially limited by single-center design or relatively small sample size …

Background Early mobilization (EM) of patients on mechanical ventilation (MV) is shown to
improve outcomes after critical illness. Little is known regarding clinician knowledge of EM …

BACKGROUND: For patients in intensive care unit (ICU), mechanical ventilation is an
effective treatment to survive from acute illness and improve survival rates. However, long …

Objectives: To evaluate the accuracy of the peroneal nerve test (PENT) in the diagnosis of
critical illness polyneuropathy (CIP) and myopathy (CIM) in the intensive care unit (ICU). We …