Dipeptidylpeptidase-4 (DPP-4) is a ubiquitously expressed transmembrane protein that
removes NH2-terminal dipeptides from various substrate hormones, chemokines …

Results Compared with healthy controls (1.82±0.16 µm), ESRD patients had a larger
perfused boundary region (+ 0.23; 95% confidence interval, 0.46 to< 0.01; P< 0.05), which …

The relationship between poor oral health and systemic diseases has been increasingly
recognized over the past two decades. Atherosclerosis is an important basal component of …

Background As patients with chronic kidney disease (CKD) are at high risk of developing
coronary artery disease (CAD), it is important to stratify their cardiovascular risk. We …

Backgroud Chronic kidney disease (CKD) is a staple risk factor not only for renal failure but
also for cardiovascular diseases. In addition, because dyslipidemia facilitates …

It is critical to understand the pathogenic role of αKlotho on the integral endothelium-
vascular smooth muscle network rather than each cell type in isolation in uremic …

Objective Renal tissue hypoperfusion and hypoxia are pivotal pathophysiological elements
in contrast media (CM)–induced acute kidney injury (AKI). According to a new paradigm of …

In advanced stages of chronic kidney disease (CKD), most patients are affected by
complications, most often correlated with cardiovascular disease (CVD)-including vascular …

Objective—Endothelial dysfunction is a possible mechanism to explain the association
between atherosclerosis and kidney disease. This study evaluated circulating soluble …

Background Chronic kidney disease is associated with increased arterial stiffness even in
the early stages and this is thought to be a key mediator in the pathophysiology of the …