Aligned neurite outgrowth and directed cell migration in self-assembled monodomain gels

EJ Berns, S Sur, L Pan, JE Goldberger, S Suresh… - Biomaterials, 2014 - Elsevier
Regeneration of neural tissues will require regrowth of axons lost due to trauma or
degeneration to reestablish neuronal connectivity. One approach toward this goal is to …

Generating new neurons to circumvent your fears: the role of IGF signaling

RC Agis-Balboa, A Fischer - Cellular and molecular life sciences, 2014 - Springer
Extinction of fear memory is a particular form of cognitive function that is of special interest
because of its involvement in the treatment of anxiety and mood disorders. Based on recent …

Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development

A Annenkov - Molecular neurobiology, 2014 - Springer
Important developmental responses are elicited in neural stem and progenitor cells (NSPC)
by activation of the receptor tyrosine kinases (RTK), including the fibroblast growth factor …

Melatonin enhances adult rat hippocampal progenitor cell proliferation via ERK signaling pathway through melatonin receptor

C Tocharus, Y Puriboriboon, T Junmanee, J Tocharus… - Neuroscience, 2014 - Elsevier
Melatonin, a neurohormone secreted mainly by the pineal gland, has a variety of
physiological functions and neuroprotective effects. Previous studies have shown that …

[HTML][HTML] Monoamine neurotransmitters and fibroblast growth factor‑2 in the brains of rats with post‑stroke depression

XW Ji, CL Wu, XC Wang, J Liu… - Experimental and …, 2014 - spandidos-publications.com
The aim of the present study was to investigate the changes in the levels of serotonin (5‑HT),
dopamine (DA), norepinephrine (NE) and fibroblast growth factor‑2 (FGF‑2) in the brains of …

Complementary Coassembling peptides: from in silico studies to in vivo application

A Raspa, GAA Saracino, R Pugliese… - Advanced Functional …, 2014 - Wiley Online Library
Selfassembling biomaterials offer an unprecedented chance of successfully facing most of
the challenges of various biomedical fields, and, in particular, of tissue engineering …

[HTML][HTML] Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells

B Bilican, MR Livesey, G Haghi, J Qiu, K Burr, R Siller… - PloS one, 2014 - journals.plos.org
Widespread use of human pluripotent stem cells (hPSCs) to study neuronal physiology and
function is hindered by the ongoing need for specialist expertise in converting hPSCs to …

Bioengineering of physiologically functional intrinsically innervated human internal anal sphincter constructs

RR Gilmont, S Raghavan, S Somara… - … Engineering Part A, 2014 - liebertpub.com
Muscle replacement for patients suffering from extensive tissue loss or dysfunction is a major
objective of regenerative medicine. To achieve functional status, bioengineered muscle …

A cGMP-applicable expansion method for aggregates of human neural stem and progenitor cells derived from pluripotent stem cells or fetal brain tissue

BC Shelley, G Gowing, CN Svendsen - JoVE (Journal of Visualized …, 2014 - jove.com
A cell expansion technique to amass large numbers of cells from a single specimen for
research experiments and clinical trials would greatly benefit the stem cell community. Many …

[HTML][HTML] Intestinal tumor in a dish

Y Ohta, T Sato - Frontiers in medicine, 2014 - frontiersin.org
Predicting the response of colorectal cancer (CRC) tumors to novel chemotherapeutic
agents is significantly complicated by their underlying genetic and epigenetic diversity …