New insights into IGF-1 signaling in the heart
Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy,
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
[HTML][HTML] Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes
Background Cardiac hypertrophy is characterized by alterations in both cardiac
bioenergetics and insulin sensitivity. Insulin promotes glucose uptake by cardiomyocytes …
bioenergetics and insulin sensitivity. Insulin promotes glucose uptake by cardiomyocytes …
Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes
Metabolic and cardiovascular disease patients have increased plasma levels of lipids and,
specifically, of palmitate, which can be toxic for several tissues. Trimetazidine (TMZ), a …
specifically, of palmitate, which can be toxic for several tissues. Trimetazidine (TMZ), a …
Role of Heterotrimeric G Protein and Calcium in Cardiomyocyte Hypertrophy Induced by IGF‐1
L Carrasco, P Cea, P Rocco… - Journal of Cellular …, 2014 - Wiley Online Library
In the heart, insulin‐like growth factor‐1 (IGF‐1) is a peptide with pro‐hypertrophic and anti‐
apoptotic actions. The pro‐hypertrophic properties of IGF‐1 have been attributed to the …
apoptotic actions. The pro‐hypertrophic properties of IGF‐1 have been attributed to the …
A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes
D Galvis-Pareja, G Zapata-Torres, J Hidalgo… - Toxicology and applied …, 2014 - Elsevier
Rationale Dihydropyridines are widely used for the treatment of several cardiac diseases
due to their blocking activity on L-type Ca 2+ channels and their renowned antioxidant …
due to their blocking activity on L-type Ca 2+ channels and their renowned antioxidant …
Influence of the toxicity of cryoprotective agents on the involvement of insulin-like growth factor-I receptor in surf clam (Spisula sachalinensis) larvae
YH Choi, TJ Nam - CryoLetters, 2014 - ingentaconnect.com
BACKGROUND: The signaling of insulin-like growth factor-I (IGF-I) is involved in the
development, growth, reproduction and aging of vertebrates. However, few studies have …
development, growth, reproduction and aging of vertebrates. However, few studies have …
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TB Igf, P Tomas-Martin, AM Lopez-Guerrero… - 2014 - academia.edu
STIM1 is a Ca 2+ sensor of the endoplasmic reticulum (ER) that triggers the activation of
plasma membrane Ca 2+ channels upon depletion of Ca 2+ levels within the ER. During …
plasma membrane Ca 2+ channels upon depletion of Ca 2+ levels within the ER. During …
New insights into IGF-1 signaling in the heart
RH Troncoso Cotal, C Ibarra, JM Vicencio… - 2014 - repositorio.uchile.cl
Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy,
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
[引用][C] Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes
JP Kuzmicic Previtali, H Verdejo Pinochet… - 2014
心臓由来幹細胞研究から想定される心臓拍動持続促進因子
川口奈奈子， 松岡瑠美子， 中西敏雄 - 日本小児循環器学会雑誌, 2014 - jstage.jst.go.jp
抄録 心筋梗塞後に低下した心機能回復のための治療に, 胚性幹細胞, induced pluripotent stem
cell (iPS 細胞), 体性幹細胞などを用いた幹細胞医療が注目されている. 胚性幹細胞および iPS …
cell (iPS 細胞), 体性幹細胞などを用いた幹細胞医療が注目されている. 胚性幹細胞および iPS …