Neurogenesis in the embryonic and adult brain: same regulators, different roles

N Urbán, F Guillemot - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Neurogenesis persists in adult mammals in specific brain areas, known as neurogenic
niches. Adult neurogenesis is highly dynamic and is modulated by multiple physiological …

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

S Sakami, AV Kolesnikov, VJ Kefalov… - Human molecular …, 2014 - academic.oup.com
Retinal rod photoreceptor cells have double membrane discs located in their outer
segments (ROS) that are continuously formed proximally from connecting cilia (CC) and …

[HTML][HTML] Cancer stem cell markers correlate with early recurrence and survival in hepatocellular carcinoma

Z Guo, LQ Li, JH Jiang, C Ou, LX Zeng… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To investigate whether expression of cancer stem cell (CSC) markers is associated with
recurrence and survival in hepatocellular carcinoma (HCC) patients. METHODS: A …

Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy

G Mohammad, J Vandooren, MM Siddiquei… - Progress in retinal and …, 2014 - Elsevier
Retinopathy, a common cause of blindness, is a hallmark of diabetes and depends on two
pathological mechanisms: vasculopathy and neuropathy. Whereas vasculopathy is well …

Validation of stem cell markers in clinical prostate cancer: α6‐Integrin is predictive for non‐aggressive disease

AM Hoogland, EI Verhoef, MJ Roobol… - The …, 2014 - Wiley Online Library
BACKGROUND Stem cells are postulated to mediate prostate cancer progression, and
represent a small fraction of the entire tumor. Various proteins (α2‐integrin, α6‐integrin …

Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas

K Holmberg Olausson, CL Maire, S Haidar, J Ling… - PloS one, 2014 - journals.plos.org
Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system
(CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to …

Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ

P Khatri, K Obernier, IK Simeonova, A Hellwig… - Scientific reports, 2014 - nature.com
Neural stem cells (NSCs) generate new neurons in vivo and in vitro throughout adulthood
and therefore are physiologically and clinically relevant. Unveiling the mechanisms …

In vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach

R Beckervordersandforth, A Deshpande, I Schäffner… - Stem cell reports, 2014 - cell.com
We describe the labeling of adult neural stem cells (aNSCs) in the mouse and human
dentate gyrus (DG) by the combinatorial expression of glial fibrillary acidic protein (GFAP) …

Human prominin-1 (CD133) is detected in both neoplastic and non-neoplastic salivary gland diseases and released into saliva in a ubiquitinated form

J Karbanova, J Laco, AM Marzesco, P Janich… - PloS one, 2014 - journals.plos.org
Prominin-1 (CD133) is physiologically expressed at the apical membranes of secretory
(serous and mucous) and duct cells of major salivary glands. We investigated its expression …

CD133 might be a pan marker of epithelial cells with dedifferentiation capacity

D Corbeil, CA Fargeas, J Jászai - Proceedings of the …, 2014 - National Acad Sciences
Kusaba et al. provide additional evidence using genetic lineage analysis that epithelial cell
dedifferentiation is responsible for repair of proximal tubules after injury in mouse (1). These …