Gut microbes and the brain: paradigm shift in neuroscience
The discovery of the size and complexity of the human microbiome has resulted in an
ongoing reevaluation of many concepts of health and disease, including diseases affecting …
ongoing reevaluation of many concepts of health and disease, including diseases affecting …
The microbiome in inflammatory bowel disease: current status and the future ahead
Studies of the roles of microbial communities in the development of inflammatory bowel
disease (IBD) have reached an important milestone. A decade of genome-wide association …
disease (IBD) have reached an important milestone. A decade of genome-wide association …
Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease
Specific members of the intestinal microbiota dramatically affect inflammatory bowel disease
(IBD) in mice. In humans, however, identifying bacteria that preferentially affect disease …
(IBD) in mice. In humans, however, identifying bacteria that preferentially affect disease …
The intestinal microbiome in early life: health and disease
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …
species abundance for about 3 years, until the microbiota becomes adult-like. During the …
[HTML][HTML] Meta-analyses of human gut microbes associated with obesity and IBD
Recent studies have linked human gut microbes to obesity and inflammatory bowel disease,
but consistent signals have been difficult to identify. Here we test for indicator taxa and …
but consistent signals have been difficult to identify. Here we test for indicator taxa and …
Potential of fecal microbiota for early‐stage detection of colorectal cancer
Several bacterial species have been implicated in the development of colorectal carcinoma
(CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer …
(CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer …
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics
MS Donia, P Cimermancic, CJ Schulze, LCW Brown… - Cell, 2014 - cell.com
In complex biological systems, small molecules often mediate microbe-microbe and microbe-
host interactions. Using a systematic approach, we identified 3,118 small-molecule …
host interactions. Using a systematic approach, we identified 3,118 small-molecule …
The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles during periods of human health and disease
HMP Integrative - Cell host & microbe, 2014 - pubmed.ncbi.nlm.nih.gov
Much has been learned about the diversity and distribution of human-associated microbial
communities, but we still know little about the biology of the microbiome, how it interacts with …
communities, but we still know little about the biology of the microbiome, how it interacts with …
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Y Haberman, TL Tickle, PJ Dexheimer… - The Journal of …, 2014 - Am Soc Clin Investig
Interactions between the host and gut microbial community likely contribute to Crohn
disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of …
disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of …
Antibiotics associated with increased risk of new-onset Crohn's disease but not ulcerative colitis: a meta-analysis
OBJECTIVES: The objective of this study was to perform a meta-analysis investigating
antibiotic exposure as a risk factor for developing inflammatory bowel disease (IBD) …
antibiotic exposure as a risk factor for developing inflammatory bowel disease (IBD) …