The IL-1 family in fish: swimming through the muddy waters of inflammasome evolution

NV Ogryzko, SA Renshaw, HL Wilson - Developmental & Comparative …, 2014 - Elsevier
Inflammatory diseases are a significant burden on global healthcare systems, and tackling
these diseases is a major focus of modern medicine. Key to many inflammatory diseases is …

Avian cytokines and chemokines

P Kaiser, P Stäheli - Avian immunology, 2014 - Elsevier
This chapter describes the current state of knowledge of avian cytokines, concentrating on
the chicken. It describes the different families of cytokines and their receptors, reagents and …

Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response

NV Ogryzko, EE Hoggett… - Disease models & …, 2014 - journals.biologists.com
ABSTRACT Interleukin-1 (IL-1), the 'gatekeeper'of inflammation, is the apical cytokine in a
signalling cascade that drives the early response to injury or infection. Expression …

The chicken IL-1 family: evolution in the context of the studied vertebrate lineage

MS Gibson, P Kaiser, M Fife - Immunogenetics, 2014 - Springer
The interleukin-1 gene family encodes a group of related proteins that exhibit a remarkable
pleiotropy in the context of health and disease. The set of indispensable functions they …

Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging

CT Primiani, VH Ryan, JS Rao, MC Cam, K Ahn… - PLoS …, 2014 - journals.plos.org
Background Age changes in expression of inflammatory, synaptic, and neurotrophic genes
are not well characterized during human brain development and senescence. Knowing …

Effect of dietary vitamin E on the growth performance and nonspecific immunity in sub-adult turbot (Scophthalmus maximus)

H Niu, Y Jia, P Hu, Z Meng, J Lei - Fish & shellfish immunology, 2014 - Elsevier
This study investigated the growth performance and non-specific immunity in sub-adult
turbot fed with graded levels of vitamin E (0, 120, 240, 480 and 960 mg kg− 1) for 15 weeks …

Comprehensive Transcriptome Profiling and Functional Analysis of the Frog (Bombina maxima) Immune System

F Zhao, C Yan, X Wang, Y Yang, G Wang, W Lee… - DNA …, 2014 - academic.oup.com
Amphibians occupy a key phylogenetic position in vertebrates and evolution of the immune
system. But, the resources of its transcriptome or genome are still little now. Bombina …

Gilthead seabream (Sparus aurata) immune responses are modulated after feeding with purified antinutrients

B Costas, A Couto, R Azeredo, M Machado… - Fish & Shellfish …, 2014 - Elsevier
The present study aimed to evaluate the effects of two purified antinutrients, soy saponins
and phytosterols, in an important species for Mediterranean aquaculture. For this purpose …

Pro-Inflammatory Cytokines in the Serum of Silver Catfish (Rhamdia quelen) Naturally Infected by Clinostomum complanatum: A Preliminary Study

HL de Lima, LM Stefani… - Journal of …, 2014 - meridian.allenpress.com
Clinostomum complanatum is a zoonotic parasite of birds, and its larval form
(metacercariae) may cause disease in fish. The immune response of fish infected by C …

[PDF][PDF] The zebrafish as a model to study the inflammasome

D Angosto, V Mulero - in vivo, 2014 - researchgate.net
Our knowledge about the inflammasome and the nucleotide-binding domain and leucine-
rich repeat containing receptor (NLR) family has increased enormously during recent years …