Suicide ranks among the leading causes of death around the world and takes a heavy
emotional and public health toll on most societies. Both distal and proximal factors contribute …

Bipolar disorder is associated with high mortality, and people with this disorder on average
may die 10–20 years earlier than the general population. This excess and premature …

Antidepressants' Black-Box Warning — 10 Years Later | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …

The FDA Warning on Antidepressants and Suicidality — Why the Controversy? | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

There is a need for a choice of scales to evaluate the full range of suicidal phenomena. Such
scales must be capable of use as both safety and efficacy outcome measures in research …

Today's medicines are regulated for their efficacy and safety and, once approved, they can
be marketed for certain uses as justified by the data. Regulatory bodies in developed …

Objective: The United States Food and Drug Administration meta-analysis of registration
trials of antidepressants found that emergent suicidality under the age of 25 years increases …

We question Lu and colleagues' findings that the prescription of antidepressants decreased
and suicide attempts in young people increased after the Food and Drug Administration …

In 2004 the US Food and Drug Administration warned that antidepressants could increase
suicidality in children and adolescents. 1 Three years later it ordered that all antidepressants …

Lu and colleagues hypothesised that US Food and Drug Administration antidepressant
safety warnings reduced antidepressant prescribing and thereby increased suicide attempts …