Candida antigens and immune responses: implications for a vaccine

MD Moragues, A Rementeria, MJ Sevilla… - Expert Review of …, 2014 - Taylor & Francis
Superficial candidiasis of the oral cavity, vagina and the skin are common mild infections
though they may be recalcitrant, as in the case of recurrent vaginitis or denture stomatitis …

[HTML][HTML] Cigarette smoke condensate increases C. albicans adhesion, growth, biofilm formation, and EAP1, HWP1 and SAP2 gene expression

A Semlali, K Killer, H Alanazi, W Chmielewski… - BMC microbiology, 2014 - Springer
Background Smokers are more prone to oral infections than are non-smokers. Cigarette
smoke reaches the host cells but also microorganisms present in the oral cavity. The contact …

[HTML][HTML] Targeted Changes of the Cell Wall Proteome Influence Candida albicans Ability to Form Single- and Multi-strain Biofilms

V Cabral, S Znaidi, LA Walker, H Martin-Yken… - PLoS …, 2014 - journals.plos.org
Biofilm formation is an important virulence trait of the pathogenic yeast Candida albicans.
We have combined gene overexpression, strain barcoding and microarray profiling to …

[HTML][HTML] Therapeutic Potential of Thiazolidinedione-8 as an Antibiofilm Agent against Candida albicans

M Feldman, A Al-Quntar, I Polacheck, M Friedman… - PloS one, 2014 - journals.plos.org
Candida albicans is known as a commensal microorganism but it is also the most common
fungal pathogen in humans, causing both mucosal and systemic infections. Biofilm …

Impact of Candida albicans hyphal wall protein 1 (HWP1) genotype on biofilm production and fungal susceptibility to microglial cells

CF Orsi, E Borghi, B Colombari, RG Neglia… - Microbial …, 2014 - Elsevier
The hyphal wall protein 1 (HWP1) gene of Candida albicans encodes for a fungal cell wall
protein, required for hyphal development and yeast adhesion to epithelial cells; yet, its role …

Effect of progesterone on Candida albicans vaginal pathogenicity

CT Alves, S Silva, L Pereira, DW Williams… - International Journal of …, 2014 - Elsevier
Candida albicans is responsible for the majority of cases of vulvovaginal candidiasis (VVC),
an infection which occurs mainly during the luteal phase of the menstrual cycle or during the …

[HTML][HTML] Human serum inhibits adhesion and biofilm formation in Candida albicans

X Ding, Z Liu, J Su, D Yan - BMC microbiology, 2014 - Springer
Background Candida albicans can form biofilms on intravenous catheters; this process plays
a key role in the pathogenesis of catheter infections. This study evaluated the effect of …

Global regulation of a differentiation MAPK pathway in yeast

CA Chavel, LM Caccamise, B Li, PJ Cullen - Genetics, 2014 - academic.oup.com
Cell differentiation requires different pathways to act in concert to produce a specialized cell
type. The budding yeast Saccharomyces cerevisiae undergoes filamentous growth in …

Inhibitory effect of verapamil on Candida albicans hyphal development, adhesion and gastrointestinal colonization

Q Yu, X Ding, B Zhang, N Xu, C Jia, J Mao… - FEMS yeast …, 2014 - academic.oup.com
Candida albicans morphogenesis and gastrointestinal colonization are closely associated
with the pathogenicity of this pathogen. This study investigated the in vitro and in vivo effect …

[PDF][PDF] N-acetylcysteine inhibits and eradicates Candida albicans biofilms

EBRM Abd, E DMMAE, GFM Gad - Am J Infect Dis Microbiol, 2014 - herniatalk.com
N-acetylcysteine (NAC) is used in the treatment of chronic bronchitis that attributed to its
mucus dissolving properties. Its ability to reduce biofilm formed by different types of bacteria …