Tobacco smoking continues to be a major global health hazard despite significant public
awareness of its harmful consequences. Although several treatment options are currently …

This review outlines the effects of 1, 2, 3, 4-tetrahydroisoquinoline (TIQ) and its derivative, 1-
methyl-1, 2, 3, 4-tetrahydroisoquinoline (1MeTIQ), endogenous substances imbued with …

Most extracellular glutamate in the brain is released by xCT, a glial antiporter that exports
glutamate and imports cystine. The function of xCT, and extracellular glutamate in general …

Addictive states are often thought to rely on lasting modification of signaling at relevant
synapses. A long-standing theory posits that activity at N-methyl-d-aspartate receptors …

Growing awareness of cerebellar involvement in addiction is based on the cerebellum's
intermediary position between motor and reward, potentially acting as an interface between …

Glutamate is known to cause the release of dopamine through a Ca 2+-sensitive mechanism
that involves activation of NMDA ionotropic glutamate receptors. In the current study, we …

No FDA approved medications currently exist for the prevention of drug craving, drug
seeking, and relapse to cocaine use. Stress is a major factor in causing relapse in cocaine …

The Disability Justice and Violence Prevention Resource Hub is funded by the CDC Rape
Prevention and Education grant distributed by the Indiana Department of Health to the …

There is evidence that drugs of abuse usurp the neurocircuitry for appetitive motivation and
reward, leading to a high comorbidity of disordered eating and substance abuse. Previous …

Quisiera mostrar mi más sentido agradecimiento a todos aquellos que contribuyeron, de
una u otra manera, a que este proyecto fuera posible. En primer lugar, y muy …