Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial

M Castro, TS King, SJ Kunselman, MD Cabana… - Jama, 2014 - jamanetwork.com
Importance In asthma and other diseases, vitamin D insufficiency is associated with adverse
outcomes. It is not known if supplementing inhaled corticosteroids with oral vitamin D 3 …

Japanese guideline for adult asthma 2014

K Ohta, M Ichinose, H Nagase, M Yamaguchi… - Allergology …, 2014 - jstage.jst.go.jp
Adult bronchial asthma (hereinafter, asthma) is characterized by chronic airway
inflammation, reversible airway narrowing, and airway hyperresponsiveness. Long-standing …

Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma

Y Zhang, DYM Leung, E Goleva - Journal of Allergy and Clinical …, 2014 - Elsevier
Background Vitamin D is known for its anti-inflammatory effects. Objective Vitamin D
regulation of responses in patients with steroid-resistant (SR) versus steroid-sensitive (SS) …

[HTML][HTML] Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma?

D Price, L Fromer, A Kaplan, T Van Der Molen… - NPJ primary care …, 2014 - nature.com
Despite current guidelines and the range of available treatments, over a half of patients with
asthma continue to suffer from poor symptomatic control and remain at risk of future …

Correlation between levels of exhaled hydrogen sulfide and airway inflammatory phenotype in patients with chronic persistent asthma

J Zhang, X Wang, Y Chen, W Yao - Respirology, 2014 - Wiley Online Library
Background and objective Endogenous hydrogen sulfide (H2S) may be a biomarker of
asthma severity and activity. However, the relationship between exhaled H2S and airway …

Designing clinical trials to address the needs of childhood and adult asthma: the National Heart, Lung, and Blood Institute's AsthmaNet

ER Sutherland, WW Busse, N Heart - Journal of allergy and clinical …, 2014 - Elsevier
In 2008, the National Heart, Lung, and Blood Institute announced its intent to support a new
asthma network known as AsthmaNet. This clinical trials consortium, now in its fifth year, has …

Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

SJH Vijverberg, R Tavendale, M Leusink… - …, 2014 - Future Medicine
Background: GLCCI1 rs37972 has previously been associated with decreased lung function
improvement upon treatment with inhaled corticosteroids (ICS) in asthmatics. Aim: To assess …

Diagnostic value of lung function parameters and FeNO for asthma in schoolchildren in large, real‐life population

T Grzelewski, K Witkowski… - Pediatric …, 2014 - Wiley Online Library
Summary Background and Objective To establish a diagnostic value of fractional exhaled
nitric oxide (FeNO), interrupter resistance measurement (Rint), specific resistance of the …

Genome-wide association study identifies ALLC polymorphisms correlated with FEV1 change by corticosteroid

TJ Park, JS Park, HS Cheong, BL Park, LH Kim… - Clinica Chimica …, 2014 - Elsevier
Objectives Asthma can be suppressed by inhaled corticosteroids (ICS). However, response
to ICS shows marked inter-individual variability. This study is aimed to identify the genetic …

Бронхиальная астма и ожирение у детей

ВП Новикова, АЭ Эглит - Вопросы детской диетологии, 2014 - elibrary.ru
Приведен обзор литературы по взаимосвязи бронхиальной астмы и ожирения у детей.
Показано, что наличие ожирения сочетается с более высокой частотой возникновения …