Gp120 in the pathogenesis of human immunodeficiency virus–associated pain
Objective Chronic pain is a common neurological comorbidity of human immunodeficiency
virus (HIV)‐1 infection, but the etiological cause remains elusive. The objective of this study …
virus (HIV)‐1 infection, but the etiological cause remains elusive. The objective of this study …
Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and …
CNS immune signaling contributes to deleterious opioid effects including hyperalgesia,
tolerance, reward, and dependence/withdrawal. Such effects are mediated by opioid …
tolerance, reward, and dependence/withdrawal. Such effects are mediated by opioid …
[HTML][HTML] Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed?
Translating promising preclinical drug discoveries to successful clinical trials remains a
significant hurdle in pain research. Although animal models have significantly contributed to …
significant hurdle in pain research. Although animal models have significantly contributed to …
[HTML][HTML] Improvement of spinal non-viral IL-10gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain
EC Dengler, LA Alberti, BN Bowman, AA Kerwin… - Journal of …, 2014 - Springer
Background Peri-spinal subarachnoid (intrathecal; it) injection of non-viral naked plasmid
DNA encoding the anti-inflammatory cytokine, IL-10 (pDNA-IL-10) suppresses chronic …
DNA encoding the anti-inflammatory cytokine, IL-10 (pDNA-IL-10) suppresses chronic …
[HTML][HTML] Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked …
Decreased voluntary wheel running has recently been proposed as a preclinical pain
measure for inflammatory pain, but whether this reflects pain evoked by use of the affected …
measure for inflammatory pain, but whether this reflects pain evoked by use of the affected …
大麻素1 型受体在大鼠子宫内膜异位病灶神经生长中的作用
赵倩倩， 梁茜子， 韩洪秀 - 中华病理学杂志, 2014 - cqvip.com
目的: 探讨大麻素1 型受体(CB1R) 在子宫内膜异位囊肿组织神经生长中的作用.
方法利用免疫荧光和免疫印迹方法检测CB1R 激动剂, 阻断剂对18 只大鼠子宫内膜异位囊肿 …
方法利用免疫荧光和免疫印迹方法检测CB1R 激动剂, 阻断剂对18 只大鼠子宫内膜异位囊肿 …
New Insights and Treatments For VZV-induced Pain In a Rat Model of Postherpetic Neuralgia
JM Guedon - 2014 - search.proquest.com
Abstract Varicella Zoster Virus is the causative agent of varicella (chickenpox) upon primary
infection and zoster (shingles) upon reactivation from latency. Viral reactivation causes …
infection and zoster (shingles) upon reactivation from latency. Viral reactivation causes …
The role of neuroglia in the development of drug dependence
M Stratilová - 2014 - dspace.cuni.cz
Drugs of abuse, such as opioids and amphetamines, represents nowadays a serious global
problem which has economical, psychological, social and medical impact. Investigation of …
problem which has economical, psychological, social and medical impact. Investigation of …