Gp120 in the pathogenesis of human immunodeficiency virus–associated pain

SB Yuan, Y Shi, J Chen, X Zhou, G Li… - Annals of …, 2014 - Wiley Online Library
Objective Chronic pain is a common neurological comorbidity of human immunodeficiency
virus (HIV)‐1 infection, but the etiological cause remains elusive. The objective of this study …

Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and …

PM Grace, KM Ramos, KM Rodgers, X Wang… - Neuroscience, 2014 - Elsevier
CNS immune signaling contributes to deleterious opioid effects including hyperalgesia,
tolerance, reward, and dependence/withdrawal. Such effects are mediated by opioid …

[HTML][HTML] Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed?

L Nicotra, J Tuke, PM Grace, PE Rolan… - Frontiers in behavioral …, 2014 - frontiersin.org
Translating promising preclinical drug discoveries to successful clinical trials remains a
significant hurdle in pain research. Although animal models have significantly contributed to …

[HTML][HTML] Improvement of spinal non-viral IL-10gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain

EC Dengler, LA Alberti, BN Bowman, AA Kerwin… - Journal of …, 2014 - Springer
Background Peri-spinal subarachnoid (intrathecal; it) injection of non-viral naked plasmid
DNA encoding the anti-inflammatory cytokine, IL-10 (pDNA-IL-10) suppresses chronic …

[HTML][HTML] Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked …

PM Grace, KA Strand, SF Maier, LR Watkins - The Journal of Pain, 2014 - Elsevier
Decreased voluntary wheel running has recently been proposed as a preclinical pain
measure for inflammatory pain, but whether this reflects pain evoked by use of the affected …

大麻素1 型受体在大鼠子宫内膜异位病灶神经生长中的作用

赵倩倩, 梁茜子, 韩洪秀 - 中华病理学杂志, 2014 - cqvip.com
目的: 探讨大麻素1 型受体(CB1R) 在子宫内膜异位囊肿组织神经生长中的作用.
方法利用免疫荧光和免疫印迹方法检测CB1R 激动剂, 阻断剂对18 只大鼠子宫内膜异位囊肿 …

New Insights and Treatments For VZV-induced Pain In a Rat Model of Postherpetic Neuralgia

JM Guedon - 2014 - search.proquest.com
Abstract Varicella Zoster Virus is the causative agent of varicella (chickenpox) upon primary
infection and zoster (shingles) upon reactivation from latency. Viral reactivation causes …

The role of neuroglia in the development of drug dependence

M Stratilová - 2014 - dspace.cuni.cz
Drugs of abuse, such as opioids and amphetamines, represents nowadays a serious global
problem which has economical, psychological, social and medical impact. Investigation of …

[引用][C] Gp120 in the pathogenesis of human HIV-associated pain

G Li, M Carlton, SK Sarna