Cognitive impairment in depression: a systematic review and meta-analysis

PL Rock, JP Roiser, WJ Riedel… - Psychological …, 2014 - cambridge.org
BackgroundThis review aimed to address the question of whether cognitive impairment
should be considered a core feature of depression that may be a valuable target for …

Cognitive dysfunction in major depressive disorder: effects on psychosocial functioning and implications for treatment

RW Lam, SH Kennedy, RS McIntyre… - … Canadian Journal of …, 2014 - journals.sagepub.com
Major depressive disorder is a common condition with a high rate of recurrence, chronicity,
and staggering economic burden, including disability in the workforce. 1 In 2010, MDD was …

Cognitive dysfunction in unipolar depression: implications for treatment

MH Trivedi, TL Greer - Journal of affective disorders, 2014 - Elsevier
Objective The primary objective of this review is to examine the literature assessing
abnormalities in neural circuitry and cognition early in the course of major depressive …

The relationship between neurocognitive and psychosocial functioning in major depressive disorder: a systematic review

VC Evans, GL Iverson, LN Yatham… - The Journal of Clinical …, 2014 - psychiatrist.com
Objective: Neurocognitive deficits are demonstrated in major depressive disorder (MDD)
and most likely contribute to the functional impairment experienced by affected individuals …

Cognitive dysfunction in major depressive disorder: a state-of-the-art clinical review

B Bortolato, AF Carvalho… - CNS & Neurological …, 2014 - ingentaconnect.com
Major depressive disorder (MDD) is a prevalent and recurring mental disorder often
associated with high rates of non-recovery and substantial consequences on psychosocial …

Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction

AL Pehrson, C Sanchez - CNS spectrums, 2014 - cambridge.org
Monoamine-based treatments for depression have evolved greatly over the past several
years, but shortcomings such as suboptimal efficacy, treatment lag, and residual cognitive …

Cognitive dysfunction in depression–pathophysiology and novel targets

AF Carvalho, KK Miskowiak… - CNS & Neurological …, 2014 - ingentaconnect.com
Major depressive disorder (MDD) is associated with cognitive dysfunction encompassing
several domains, including memory, executive function, processing speed and attention …

Recombinant human erythropoietin for treating treatment-resistant depression: a double-blind, randomized, placebo-controlled phase 2 trial

KW Miskowiak, M Vinberg, EM Christensen… - …, 2014 - nature.com
Pharmacological treatments for depression have insufficient efficacy in 30–40% of patients
and fail to reverse cognitive deficits. Erythropoietin (EPO) has neurotrophic actions and aids …

More rumination and less effective emotion regulation in previously depressed women with preserved executive functions

M Aker, C Harmer, NI Landrø - Bmc Psychiatry, 2014 - Springer
Background Major depressive disorder is associated with very high recurrence rates, and
specific vulnerability factors that increase the risk for repeated episodes should be identified …

Systematic review of appropriate cognitive assessment instruments used in clinical trials of schizophrenia, major depressive disorder and bipolar disorder

N Bakkour, J Samp, K Akhras, E El Hammi, I Soussi… - Psychiatry …, 2014 - Elsevier
Cognitive dysfunction is increasingly recognized as a symptom in mental conditions
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BPD) …