PRC1 complex diversity: where is it taking us?

J Gil, A O'Loghlen - Trends in cell biology, 2014 - cell.com
Polycomb group proteins (PcGs) are essential epigenetic regulators that play key roles in
development, pluripotency, senescence, and cancer. Recent reports have found that the …

An AUTS2–Polycomb complex activates gene expression in the CNS

Z Gao, P Lee, JM Stafford, M Von Schimmelmann… - Nature, 2014 - nature.com
Naturally occurring variations of Polycomb repressive complex 1 (PRC1) comprise a core
assembly of Polycomb group proteins and additional factors that include, surprisingly …

H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology

JI Belle, A Nijnik - The international journal of biochemistry & cell biology, 2014 - Elsevier
Posttranslational modifications of histone H2A through the attachment of ubiquitin or poly-
ubiquitin conjugates are common in mammalian genomes and play an important role in the …

The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment

W Yang, YH Lee, AE Jones, JL Woolnough… - Nature …, 2014 - nature.com
Abstract Polycomb Repressive Complex 1 and histone H2A ubiquitination (ubH2A)
contribute to embryonic stem cell (ESC) pluripotency by repressing lineage-specific gene …

Checks and balances between cohesin and polycomb in gene silencing and transcription

D Dorsett, JA Kassis - Current Biology, 2014 - cell.com
The cohesin protein complex was discovered for its roles in sister chromatid cohesion and
segregation, and the Polycomb group (PcG) proteins for their roles in epigenetic gene …

[HTML][HTML] AUTS2 confers gene activation to Polycomb group proteins in the CNS

Z Gao, P Lee, JM Stafford, M von Schimmelmann… - Nature, 2014 - ncbi.nlm.nih.gov
Naturally occurring variations of Polycomb Repressive Complex 1 (PRC1) comprise a core
assembly of Polycomb group proteins and additional factors that include, surprisingly …

USP16 and Histone H2A Deubiquitination in Mouse Embryonic Stem Cell Function

W Yang - 2014 - digitalcommons.library.uab.edu
In eukaryotic cells, genomic DNA is packaged into a chromatin structure by association with
histone and non-histone proteins. Posttranslational modifications of histones play important …

[HTML][HTML] Cohesin and Polycomb: Cooperative Checks and Balances in Gene Silencing and Transcription

D Dorsett, JA Kassis - Current biology: CB, 2014 - ncbi.nlm.nih.gov
The cohesin protein complex was discovered for its roles in sister chromatid cohesion and
segregation, and the Polycomb group (PcG) proteins for their roles in epigenetic gene …

[引用][C] BAP1 Deubiquitinase Antagonizes Ubiquitin-Mediated Activation of FoxK2 Target Genes

Y Okino, Y Machida, S Frankland-Searby, YJ Machida - peptides, 2014 - ASBMB