[HTML][HTML] Pharmacokinetic aspects and in vitro–in vivo correlation potential for lipid-based formulations

S Kollipara, RK Gandhi - Acta Pharmaceutica Sinica B, 2014 - Elsevier
Lipid-based formulations have been an attractive choice among novel drug delivery systems
for enhancing the solubility and bioavailability of poorly soluble drugs due to their ability to …

Solid self-microemulsifying drug delivery system of ritonavir

A Deshmukh, S Kulkarni - Drug development and industrial …, 2014 - Taylor & Francis
Context: Ritonavir (RTV) is a human immunodeficiency virus (HIV) protease inhibitor (PI)
with activity against HIV, practically insoluble in water and recommended to co-administer as …

An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in danazol bioavailability from …

MU Anby, TH Nguyen, YY Yeap… - Molecular …, 2014 - ACS Publications
The impact of gastrointestinal (GI) processing and first pass metabolism on danazol oral
bioavailability (BA) was evaluated after administration of self-emulsifying drug delivery …

[HTML][HTML] Role of medium-chain fatty acids in the emulsification mechanistics of self-micro-emulsifying lipid formulations

NMY Hasan - Saudi Pharmaceutical Journal, 2014 - Elsevier
Purpose The objective of the present study was to design and develop stable o/w
microemulsions comprising Miglyol 812, Imwitor 988 and Tagat TO as a non ionic surfactant …

Feasibility of capsule endoscopy for direct imaging of drug delivery systems in the fasted upper-gastrointestinal tract

PB Pedersen, D Bar-Shalom, S Baldursdottir… - Pharmaceutical …, 2014 - Springer
Purpose To develop a minimally-invasive method for direct visualization of drug delivery
systems in the human stomach and to compare the obtained results with an established in …

Maximized mucoadhesion and skin permeation of anti-AIDS-loaded niosomal gels

AS Zidan, MJ Habib - Journal of Pharmaceutical Sciences, 2014 - Elsevier
The low permeability of the anti-AIDS, tenofovir, limits its antiretroviral clinical potency. The
proposed study aimed at assessing the critical biological responses of tenofovir through the …

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

N Heshmati, X Cheng, E Dapat… - Journal of Pharmacy …, 2014 - academic.oup.com
Objectives Anticancer indirubins are poorly soluble in water. Here, digestion of four self-
emulsifying drug delivery systems (SEDDS) containing E804 (indirubin-3′-oxime 2, 3 …

[PDF][PDF] Formulation and development of self-microemulsifying drug delivery system of pioglitazone

JR Madan, B Sudarshan… - Asian Journal of …, 2014 - asiapharmaceutics.info
System (BCS) class II drugs. The current research aimed to improve the dissolution of poorly
water-soluble antidiabetic drug pioglitazone HCl by formulating it in SMEDDS. Liquid …

Enhanced dissolution of repaglinide: SMEDDS formulation and in-vitro evaluation

H Ponnaganti, K Abbulu - Research Journal of Pharmacy and …, 2014 - indianjournals.com
Repaglinide a BCS class II poorly water soluble drug was formulated into lipid drug delivery
system of self microemulsifying delivery system (SMEDDS). Surfactants and oil was selected …

Effect of oils and surfactants on physicochemical characterization and in vitro dissolution of glibenclamide from self-emulsifying formulations

F Shakeel, N Haq, FK Alanazi, IA Alsarra - Journal of Drug Delivery Science …, 2014 - Elsevier
The aim of present study was to investigate the impact of various excipients (oil type and
nonionic surfactants) having same composition on physicochemical characterization and …