Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …

Dividing cells almost always adopt a spherical shape. This is true of most eukaryotic cells
lacking a rigid cell wall and is observed in tissue culture and single-celled organisms, as …

Abstract Development of increasingly complex integrated cellular systems will be a major
challenge for the next decade and beyond, as we apply the knowledge gained from the sub …

Characterizing the physical properties of single cells is of great interest for unraveling the
heterogeneity in a cell population. Recent advances in micro-systems technologies and …

The detection and treatment of cancer has advanced significantly in the past several
decades, with important improvements in our understanding of the fundamental molecular …

The density of a single cell is a fundamental property of cells. Cells in the same cycle phase
have similar volume, but the differences in their mass and density could elucidate each cell's …

Despite continuing research efforts, timely and simple pathogen detection with a high
degree of sensitivity and specificity remains an elusive goal. Given the recent explosion of …

Originally invented for topographic imaging, atomic force microscopy (AFM) has evolved into
a multifunctional biological toolkit, enabling to measure structural and functional details of …

Granular packing of microsized particles with different size distributions and contact force
models is studied using discrete element method (DEM). Three kinds of size distributions …

This paper develops a simple continuation method for the approximate solution of optimal
control problems. The class of optimal control problems considered include (i) problems with …