[HTML][HTML] Axonal pathology and demyelination in viral models of multiple sclerosis

JE Libbey, TE Lane, RS Fujinami - Discovery medicine, 2014 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of the
central nervous system (CNS). Monozygotic twin studies suggest that while there is a …

Adaptive immune response to viral infections in the central nervous system

JE Libbey, RS Fujinami - Handbook of clinical neurology, 2014 - Elsevier
This chapter provides an overview of the adaptive immune response to viral infection
outside of and within the central nervous system (CNS). It begins with a description of the …

Progression From IgD+ IgM+ to Isotype-Switched B Cells Is Site Specific during Coronavirus-Induced Encephalomyelitis

TW Phares, KD DiSano, SA Stohlman… - Journal of …, 2014 - Am Soc Microbiol
Various infections in the central nervous system (CNS) trigger B cell accumulation; however,
the relative dynamics between viral replication and alterations in distinct B cell subsets are …

[HTML][HTML] FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination

CA Blanc, H Rosen, TE Lane - Journal of neuroinflammation, 2014 - Springer
Background FTY720 (fingolimod) is the first oral drug approved by the Food and Drug
Administration for treatment of patients with the relapsing-remitting form of the human …

[图书][B] T cell responses to S-glutathionylated And heteroclitic viral epitopes and CCl2-mediated immune dysregulation in mice infected with a neurotropic coronavirus

JA Trujillo - 2014 - search.proquest.com
Mice infected with neurotropic variants of the murine coronavirus, mouse hepatitis
virus,(strains JHMV or J2. 2–V–1) develop acute and chronic CNS infections, and provide a …