The Wnt (wingless-type) signaling pathway plays an important role in embryonic
development, tissue homeostasis, and tumor progression becaluse of its effect on cell …

Proteins, RNAs and viruses can be spread through exosomes, therefore transport utilizing
these nanovesicles is of the great interest. MiRNAs are common exosomal constituents …

Posttranscriptional maturation is a critical step in microRNA (miRNA) biogenesis that
determines mature miRNA levels. In addition to core components (Drosha and DGCR8 …

Introduction MicroRNAs (miRs) play important roles in the development and progression of
human cancers. MiR-146a down-regulates epidermal growth factor receptor and the nuclear …

Primary ovarian insufficiency (POI) is a serious reproductive dysfunction in which the follicle
pool is reduced and depleted. Abnormal apoptosis of ovarian granulosa cells (GCs) is …

MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular
processes. Their deregulation is thus often causative of human malignancies, including …

There is limited understanding of how radiation or chemicals induce genomic instability, and
how the instability is epigenetically transmitted to the progeny of exposed cells or organisms …

Accumulating evidence has indicated that microRNAs (miRNAs or miRs) play important
roles in the developing rat brain. In this study, we investigated the role of miRNAs in the …

Cancer remains a major health problem and is one of the leading causes of deaths
worldwide. It is a complex disease which can originate from several causes, and genome …

The increasing aging population in all developed countries is causing an increase in the
number of people suffering from age-related chronic inflammatory diseases such as arthritis …