Leishmaniasis remains a major public health problem worldwide and is classified as
Category I by the TDR/WHO, mainly due to the absence of control. Many experimental …

Leishmaniasis covers a broad spectrum of diseases with distinct, and sometimes
overlapping, characteristics. The common thread in all forms of leishmaniasis is the infection …

Asymptomatic Leishmania Infection: A New Challenge for Leishmania Control | Clinical
Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an
estimated 1.5 million new cases per year. In Brazil, ACL represents a significant public …

Parasites still impose a high death and disability burden on human populations, and are
therefore likely to act as selective factors for genetic adaptations. Genetic epidemiological …

Crucial to the defense against Leishmania is the ability of the host to mount a cell-mediated
immune response capable of controlling and/or eliminating the parasite. The composition of …

In visceral leishmaniasis (VL) endemic areas, a minority of infected individuals progress to
disease since most of them develop protective immunity. Therefore, we investigated the risk …

Human visceral leishmaniasis is endemic in the Mediterranean basin. Since most infections
are sub-clinical or asymptomatic, host genetics can provide concrete evidence in …

The use of toll-like receptor agonists in immunotherapy is a new approach in the prevention
of immunosuppression during fatal Leishmania parasite infection. The objective of such …

Macrophages play a vital role in early defense against pathogens and are required for tissue
repair following injury. In response to various stimuli, macrophages become …