[HTML][HTML] Astrogliosis as a therapeutic target for neurodegenerative diseases

AM Colangelo, L Alberghina, M Papa - Neuroscience letters, 2014 - Elsevier
Chronic neurodegenerative diseases represent major unmet needs for therapeutic
interventions. Recently, the neurocentric view of brain function and disease has been …

Astrocyte–neuron interplay in maladaptive plasticity

M Papa, C De Luca, F Petta, L Alberghina… - … & Biobehavioral Reviews, 2014 - Elsevier
The complexity of neuronal networks cannot only be explained by neuronal activity so
neurobiological research in the last decade has focused on different components of the …

Presentation of BMP-2 mimicking peptides in 3D hydrogels directs cell fate commitment in osteoblasts and mesenchymal stem cells

CM Madl, M Mehta, GN Duda, SC Heilshorn… - …, 2014 - ACS Publications
Many strategies for controlling the fate of transplanted stem cells rely on the concurrent
delivery of soluble growth factors that have the potential to produce undesirable secondary …

Assessment methods for angiogenesis and current approaches for its quantification

WH AlMalki, I Shahid, AY Mehdi… - Indian journal of …, 2014 - journals.lww.com
Angiogenesis is a physiological process which describes the development of new blood
vessels from the existing vessels. It is a common and the most important process in the …

[HTML][HTML] A novel dimeric dipeptide mimetic of the nerve growth factor exhibits pharmacological effects upon systemic administration and has no side effects …

TA Gudasheva, PY Povarnina, TA Antipova… - Neuroscience & …, 2014 - scirp.org
The development of small molecule nerve growth factor (NGF) mimetics is a promising
approach to overcome limitations in the use of the neurotrophin as a drug, which are poor …

Mechanisms of neurotrophic and neuroprotective effects of cerebrolysin in cerebral ischemia

OA Gromova, T IIu, IV Gogoleva - Zhurnal Nevrologii i Psikhiatrii …, 2014 - europepmc.org
Cerebrolysin is the drug which contains peptides derived from the brain of a pig. It is used in
neurological practice for recovery of stroke patients and treatment of dementia. Despite the …

Оригинальный дипептидный миметик фактора роста нервов ГК-2 избирательно активирует пострецепторные пути ТrkA, не вызывая побочных действий …

ТА Гудашева, ТА Антипова… - Доклады Академии …, 2014 - elibrary.ru
ГУДАШЕВА и др. культуре DRG нейронов крысы. На клетках ли нии PC12 было
показано, что МТ2 вызывает фос форилирование тирозина 490 TrkA рецепторов и …

Methods of use of Trk receptor modulators

HU Saragovi - US Patent 8,648,169, 2014 - Google Patents
The present invention relates to methods of treating or pre venting retinal ganglion cell
(RGC) death and/or glaucoma using modulators of neurotrophic receptors that comprise B …

Nerve growth factor novel dipeptide mimetic GK-2 selectively activates TrkA postreceptor signaling pathways and does not cause adverse effects of native …

TA Gudasheva, TA Antipova… - Doklady …, 2014 - search.proquest.com
Nerve growth factor (NGF), the first of the family of neurotrophins [1], has been attracting
attention as a possible medicine for treatment for acute cerebrovas cular events and a …

神经生长因子致痛机制的研究进展

罗妮, 郑卫红 - 广东医学, 2014 - cqvip.com
疼痛根据其神经生理学机制可分为感受性疼痛和神经病理性疼痛两类, 前者直接由伤害性刺激
引起, 与组织损伤或炎症反应有关, 又称炎症性疼痛; 后者由躯体感觉神经系统的损伤或疾病直接 …