[HTML][HTML] Genetic predisposition to colorectal cancer: where we stand and future perspectives
L Valle - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
The development of colorectal cancer (CRC) can be influenced by genetic factors in both
familial cases and sporadic cases. Familial CRC has been associated with genetic changes …
familial cases and sporadic cases. Familial CRC has been associated with genetic changes …
[HTML][HTML] Long non-coding RNAs in colorectal cancer: implications for pathogenesis and clinical application
M Xu, P Qi, X Du - Modern pathology, 2014 - Elsevier
Long non-coding RNAs (lncRNAs) are a class of newly identified non-coding RNA
molecules that are emerging as key regulators of tumor initiation and development …
molecules that are emerging as key regulators of tumor initiation and development …
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk
Known genetic loci explain only a small proportion of the familial relative risk of colorectal
cancer (CRC). We conducted a genome-wide association study of CRC in East Asians with …
cancer (CRC). We conducted a genome-wide association study of CRC in East Asians with …
CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer
The prognosis of non-small cell lung cancer (NSCLC) is still poor, and it is necessary to
identify effectively diagnostic and prognostic biomarkers for NSCLC. Recent evidence …
identify effectively diagnostic and prognostic biomarkers for NSCLC. Recent evidence …
Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5
The mechanism by which the 8q24 MYC enhancer region, including cancer-associated
variant rs6983267, increases cancer risk is unknown due to the lack of protein-coding genes …
variant rs6983267, increases cancer risk is unknown due to the lack of protein-coding genes …
Estimating the heritability of colorectal cancer
A sizable fraction of colorectal cancer (CRC) is expected to be explained by heritable
factors, with heritability estimates ranging from 12 to 35% twin and family studies. Genome …
factors, with heritability estimates ranging from 12 to 35% twin and family studies. Genome …
[HTML][HTML] Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region
Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously
identified human leukocyte antigen (HLA) gene variants. To identify additional FL …
identified human leukocyte antigen (HLA) gene variants. To identify additional FL …
Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence
X Ma, B Zhang, W Zheng - Gut, 2014 - gut.bmj.com
Objective In the past two decades, approximately 1000 reports have been published
regarding associations between genetic variants in candidate genes and risk of colorectal …
regarding associations between genetic variants in candidate genes and risk of colorectal …
[HTML][HTML] Genome-wide diet-gene interaction analyses for risk of colorectal cancer
Dietary factors, including meat, fruits, vegetables and fiber, are associated with colorectal
cancer; however, there is limited information as to whether these dietary factors interact with …
cancer; however, there is limited information as to whether these dietary factors interact with …
Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis
In this study, we aim to identify the genes responsible for colorectal cancer risk behind the
loci identified in genome-wide association studies (GWAS). These genes may be candidate …
loci identified in genome-wide association studies (GWAS). These genes may be candidate …