The National Kidney Foundation–Kidney Disease Outcomes Quality Initiative (NKF-KDOQI)
guideline for evaluation, classification, and stratification of chronic kidney disease (CKD) …

In children, hypophosphatemic rickets (HR) is revealed by delayed walking, waddling gait,
leg bowing, enlarged cartilages, bone pain, craniostenosis, spontaneous dental abscesses …

An elevated level of fibroblast growth factor-23 (FGF-23) is the earliest abnormality of
mineral metabolism in CKD. High FGF-23 levels promote left ventricular hypertrophy but not …

Abstract Fibroblast growth factor‐23 (FGF 23) is a bone‐derived hormone regulating renal
phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here, we show …

Fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) signaling plays
essential roles in bone development and diseases. Missense mutations in FGFs and FGFRs …

Introduction. Heart failure (HF) is highly prevalent in patients with chronic kidney disease
(CKD) and end-stage renal disease (ESRD) and is strongly associated with mortality in …

Background: Elevated serum phosphorus is associated with all-cause mortality, but little is
known about risk associated with dietary phosphorus intake. Objective: We investigated the …

Disturbances in phosphate homeostasis are common in patients with chronic kidney
disease. As kidney function declines, circulating concentrations of phosphate and the …

Iron deficiency stimulates FGF23 production, but normal osteocytes couple increased FGF23
production with increased cleavage to maintain normal circulating levels of biologically …

Fibroblast growth factor 23 (FGF23) is secreted primarily by osteocytes and regulates
phosphate and vitamin D metabolism. Elevated levels of FGF23 are clinically associated …