The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …

After spinal cord injury (SCI) there is prolonged and dispersed oligodendrocyte cell death
that is responsible for widespread demyelination. To regenerate this lost myelin, many …

Background Acute spinal cord injury (ASCI) is a catastrophic event that can profoundly affect
the trajectory of a patient's life. Debate continues over the pharmacologic management of …

Apoptosis has been widely reported to be involved in the pathogenesis associated with
spinal cord injury (SCI). Recently, autophagy has also been implicated in various neuronal …

Spinal cord injury can have a range of debilitating effects, permanently impacting a patient's
quality of life. Initially thought to be an immune privileged site, the spinal cord is able to …

The Wnt family of proteins plays key roles during central nervous system development and
has been involved in several neuropathologies during adulthood, including spinal cord …

Self-assembling peptides are promising biomaterials for spinal cord repair as they can
easily be injected into the lesion site and can provide physical support to regrowing nervous …

Spinal cord injury (SCI) often results in irreversible and permanent neurological deficits and
long-term disability. Vasospasm, hemorrhage, and loss of microvessels create an ischemic …

In this study, neuroprotective effect of tamoxifen has been explored in spinal cord injury
(SCI) in rats by examining factors influencing IKK/NF-kB pathway in SCI in rats. It has been …

Clinical studies have shown that hyperbaric oxygen therapy improves motor function in
patients with spinal cord injury. In the present study, we explored the mechanisms …