Familial aggregation and the studies of twins indicate that heredity contributes to multiple
sclerosis (MS) risk. Immunologic studies of leukocyte antigens subsequently followed by …

The pathogenesis of multiple sclerosis (MS) is as yet unknown. Commonly, MS is assumed
to be due to an autoimmune inflammation of the central nervous system (CNS) …

Background: Many genetic risk variants are now well established in multiple sclerosis (MS),
but the impact on clinical phenotypes is unclear. Objective: To investigate the impact of …

Background Abnormal intrathecal synthesis of IgG, reflected by cerebrospinal fluid (CSF)
oligoclonal IgG bands (OBs) and increased IgG index, is much less frequently observed in …

Background: A large portion of existing medical research on Multiple Sclerosis patients
focuses more on predicting medical variables (such as diagnosis, treatment) and individual …

Abstract The Latin American MS Experts' Forum has developed practical recommendations
on the initiation and optimization of disease-modifying therapies in patients with relapsing …

Multiple sclerosis (MS) patients are classified as either having relapsing onset or
progressive onset disease, also known as primary progressive MS (PPMS). Relative to …

Susceptibility to multiple sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with
the HLA-DR15 haplotype (DRB1* 1501-DQA1* 0102-DQB1* 0602-DRB5* 0101) dominating …

Objectives: To investigate whether (1) there were differences between HLA-DRB1* 15-
positive and-negative patients at baseline, and (2) HLA-DRB1* 15-positive patients showed …

Neuromyelitis optica (NMO) and multiple sclerosis (MS) are both autoimmune inflammatory
and demyelinating disorders of the central nervous system. Recently, more than 50 MS …