A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data
High-throughput sequencing of related individuals has become an important tool for
studying human disease. However, owing to technical complexity and lack of available tools …
studying human disease. However, owing to technical complexity and lack of available tools …
[HTML][HTML] Identifying rare variants for genetic risk through a combined pedigree and phenotype approach: application to suicide and asthma
Suicidal behavior is a complex disorder, with evidence for genetic risk independent of other
genetic risk factors including psychiatric disorders. Since 1996, over 3000 DNA samples …
genetic risk factors including psychiatric disorders. Since 1996, over 3000 DNA samples …