Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of central nerve system metastases from non-small cell lung cancer

J Zhang, J Yu, X Sun, X Meng - Cancer letters, 2014 - Elsevier
Brain metastases (BM) are common and disastrous occurrence in patients with non-small
cell lung cancer (NSCLC). Currently increasing studies suggest remarkable efficacy and …

Randomized trial of erlotinib plus whole-brain radiotherapy for NSCLC patients with multiple brain metastases

SM Lee, CR Lewanski, N Counsell… - JNCI: Journal of the …, 2014 - academic.oup.com
Background Median survival of non-small cell lung cancer (NSCLC) patients with brain
metastases is poor. We examined concurrent erlotinib and whole brain radiotherapy (WBRT) …

[PDF][PDF] High-dose, weekly erlotinib is not an effective treatment in EGFR-mutated non-small cell lung cancer-patients with acquired extracranial progressive disease on …

JL Kuiper, DA Heideman, E Thunnissen, AW van Wijk… - Eur J …, 2014 - academia.edu
Resistance to tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC)-
patients with an epidermal growth factor (EGFR) mutation is a major clinical problem …

Long term therapeutic plan for patients with non-small cell lung cancer harboring EGFR mutation

SH Jang - Tuberculosis and Respiratory Diseases, 2014 - synapse.koreamed.org
Non-small cell lung cancer harboring epidermal growth factor receptor (EGFR) sensitizing
mutations has a distinct disease entity. Patients with this cancer have better prognosis, and …

非小细胞肺癌脑转移药物治疗的研究进展

蔡忠福, 欧阳学农, 余宗阳 - 临床肿瘤学杂志, 2014 - manu65.magtech.com.cn
非小细胞肺癌(NSCLC) 是最常见的恶性肿瘤之一, 也是导致癌症死亡的主要原因, 其疗效欠佳,
预后差, 尤其是伴有脑转移患者. NSCLC 伴脑转移患者生活质量差, 预后不良 …

Favorable response to icotinib in a lung cancer patient with a special mutation at exon 19 of epidermal growth factor receptor

H Zheng, Q Wang, H Shi, H Zhang, F Hu… - Thoracic Cancer, 2014 - Wiley Online Library
Many studies have illustrated that two types of mutation–deletions in exon 19 and a point
mutation in exon 21 (L858R)–have been reported to comprise up to 90% of all activating …

[PDF][PDF] Journal of Thoracic Oncology Publish Ahead of Print

MD Märten, RM Huber, NJ Dickgreber - academia.edu
Introduction: Afatinib is an effective first-line treatment in patients with epidermal growth
factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) and has shown activity …

[引用][C] 表皮生长因子受体-酪氨酸激酶抑制剂对非小细胞肺癌患者中枢神经系统转移的疗效

王孟昭, 陈闽江 - 中华结核和呼吸杂志, 2014

[引用][C] 非小细胞肺癌脑转移厄洛替尼结合全脑放疗治疗的理论基础和研究进展

朱虹, 李云海, 王洪林, 赵森 - 国际肿瘤学杂志, 2014

[引用][C] 脑转移瘤的内科治疗

周生渝 - 中国临床医生杂志, 2014