Targeting antioxidants for cancer therapy
A Glasauer, NS Chandel - Biochemical pharmacology, 2014 - Elsevier
Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …
production and an altered redox environment compared to normal cells. Furthermore, redox …
Molecular mechanisms underlying chronic inflammation-associated cancers
Y Wu, S Antony, JL Meitzler, JH Doroshow - Cancer letters, 2014 - Elsevier
Highlights•Redox-related transcription factor upregulation characterizes inflammation-
related cancer.•NADPH oxidase-dependent ROS are associated with inflammation and …
related cancer.•NADPH oxidase-dependent ROS are associated with inflammation and …
Investigation of angiogenesis and its mechanism using zinc oxide nanoparticle-loaded electrospun tissue engineering scaffolds
R Augustine, EA Dominic, I Reju, B Kaimal… - Rsc Advances, 2014 - pubs.rsc.org
Angiogenesis through tissue engineering scaffolds is an important factor that determines the
success of a tissue engineering endeavor. Zinc oxide (ZnO) nanoparticles are well known …
success of a tissue engineering endeavor. Zinc oxide (ZnO) nanoparticles are well known …
NADPH oxidases: a perspective on reactive oxygen species production in tumor biology
JL Meitzler, S Antony, Y Wu, A Juhasz… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Reactive oxygen species (ROS) promote genomic instability, altered signal
transduction, and an environment that can sustain tumor formation and growth. The NOX …
transduction, and an environment that can sustain tumor formation and growth. The NOX …
[HTML][HTML] Pattern-recognition receptors and gastric cancer
N Castaño-Rodríguez, NO Kaakoush… - Frontiers in …, 2014 - frontiersin.org
Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …
Reactive oxygen species: physiological roles in the regulation of vascular cells
Reactive oxygen species (ROS) are now appreciated to play several important roles in a
number of biological processes and regulate cell physiology and function. ROS are a …
number of biological processes and regulate cell physiology and function. ROS are a …
[HTML][HTML] Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer
Background: The purpose of this study was to confirm that RRM2 as a novel target of HPVE7
involved in cervical cancer angiogenesis. Methods: Gene expression was analysed by RT …
involved in cervical cancer angiogenesis. Methods: Gene expression was analysed by RT …
[PDF][PDF] Free radicals, antioxidants and disease
N Sharma - Biology and Medicine, 2014 - Citeseer
Living cells continually generate free radicals or reactive oxygen species (ROS) through the
respiratory chain during energetic metabolism. ROS can either be harmful or play important …
respiratory chain during energetic metabolism. ROS can either be harmful or play important …
[HTML][HTML] The role of reactive oxygen species in microvascular remodeling
MC Staiculescu, C Foote, GA Meininger… - International journal of …, 2014 - mdpi.com
The microcirculation is a portion of the vascular circulatory system that consists of resistance
arteries, arterioles, capillaries and venules. It is the place where gases and nutrients are …
arteries, arterioles, capillaries and venules. It is the place where gases and nutrients are …
Mitochondrial dysfunction in cancer
K Księżakowska-Łakoma, M Żyła… - Menopause Review …, 2014 - termedia.pl
Mitochondria are semi-autonomous organelles of eukaryotic cells. They perform crucial
functions such as generating most of the cellular energy through the oxidative …
functions such as generating most of the cellular energy through the oxidative …