The human papillomavirus family and its role in carcinogenesis

M Tommasino - Seminars in cancer biology, 2014 - Elsevier
Human papillomaviruses (HPVs) are a family of small double-stranded DNA viruses that
have a tropism for the epithelia of the genital and upper respiratory tracts and for the skin …

[HTML][HTML] Update on prevention and screening of cervical cancer

SL McGraw, JM Ferrante - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
Cervical cancer is the third most common cause of cancer in women in the world. During the
past few decades tremendous strides have been made toward decreasing the incidence …

Review of the current knowledge on the epidemiology, pathogenesis, and prevention of human papillomavirus infection

A Asiaf, ST Ahmad, SO Mohammad… - European Journal of …, 2014 - journals.lww.com
Human papillomavirus (HPV) infection is a central and necessary, although not sufficient,
cause of cervical cancer. Besides HPV, the additional multiple risk factors related with the …

Human papillomavirus genomics: past, present and future

A Harari, Z Chen, RD Burk - Human papillomavirus, 2014 - karger.com
Human papillomaviruses (HPV) are a group of divergent DNA viruses, of which a select few
evolutionarily related HPVs have emerged to be highly oncogenic and of significant medical …

Chlamydia trachomatis and risk of cervical intraepithelial neoplasia grade 3 or worse in women with persistent human papillomavirus infection: a cohort study

KE Jensen, LT Thomsen, S Schmiedel… - Sexually transmitted …, 2014 - sti.bmj.com
Objectives Some studies suggest that Chlamydia trachomatis (CT) enhances cervical
carcinogenesis; however, a possible confounding effect of persistent human papillomavirus …

A prospective study of age trends of high-risk human papillomavirus infection in rural China

LN Kang, PE Castle, FH Zhao, J Jeronimo… - BMC infectious …, 2014 - Springer
Abstract Background In China, high-risk human papillomavirus (HR-HPV) prevalence is
unexpectedly high in older women, but the possible reasons have not been well studied yet …

The epidemiology of human papillomaviruses

AG Nyitray, MR Iannacone - Human Papillomavirus, 2014 - karger.com
Epidemiological studies indicate that most men and women will acquire a sexually
transmitted anogenital human papillomavirus (HPV) infection in their lifetimes. In addition …

Safety of an Escherichia coli-expressed bivalent human papillomavirus (types 16 and 18) L1 virus-like particle vaccine: An open-label phase I clinical trial

YM Hu, SJ Huang, K Chu, T Wu, ZZ Wang… - Human vaccines & …, 2014 - Taylor & Francis
An Escherichia coli-expressed recombinant bivalent human papillomavirus (types 16 and
18) vaccine candidate has been shown to be safe and immunogenic in preclinical trials. The …

Immunosuppression in cervical cancer with special reference to arginase activity

AM Bedoya, DJ Tate, A Baena, CM Córdoba… - Gynecologic …, 2014 - Elsevier
Introduction Cervical cancer is characterized by an immunosuppressive microenvironment
and a Th2-type cytokine profile. Expression of arginase (ASE), the enzyme that converts l …

Persistence, clearance and reinfection regarding six high risk human papillomavirus types in Colombian women: a follow-up study

SC Soto-De León, L Del Río-Ospina, M Camargo… - BMC infectious …, 2014 - Springer
Background The design of new healthcare schemes which involve using molecular HPV
screening means that both persistence and clearance data regarding the most prevalent …