Recognized as a “disease modifier”, physical activity (PA) is increasingly viewed as a more
holistic, cost-saving method for prevention, treatment and management of human disease …

The purpose of this study was to examine opioid and endocannabinoid mechanisms of
exercise-induced hypoalgesia (EIH). Fifty-eight men and women (mean age= 21 years) …

Nitric oxide (NO) is a soluble gas that participates in important functions of the central
nervous system, such as cognitive function, maintenance of synaptic plasticity for the control …

Purpose: To outline the potential mechanisms and experimental limitations for exercise-
induced pain inhibition. Methods: Investigations that applied physical exertion to evoke …

OBJECTIVE: To investigate the involvement of opioid receptors in antinociception induced
by different aerobic exercise protocols in rats. METHODS: This experimental study …

Orexins (orexin-A and-B) are neuropeptides with multiple physiological functions, among
which regulation of wakefulness and appetite are the best known. Neurons producing …

Os endocanabinóides são sintetizados e liberados da membrana dos neurônios pós-
sinápticos segundo a demanda, após o influxo de cálcio (1). Eles ativam os receptores pré …

The primary objective of this PhD thesis was to investigate the temporal and spatial
manifestations of exercise-induced hypoalgesia (EIH) and conditioned pain modulation …