The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
[HTML][HTML] Neuroinflammation after intracerebral hemorrhage
E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …
no specific treatment has been established yet. Although preclinical models of ICH have …
Metastasis review: from bench to bedside
Cancer is the final result of uninhibited cell growth that involves an enormous group of
associated diseases. One major aspect of cancer is when cells attack adjacent components …
associated diseases. One major aspect of cancer is when cells attack adjacent components …
Mathematical modelling of cancer invasion: implications of cell adhesion variability for tumour infiltrative growth patterns
P Domschke, D Trucu, A Gerisch… - Journal of theoretical …, 2014 - Elsevier
Cancer invasion, recognised as one of the hallmarks of cancer, is a complex, multiscale
phenomenon involving many inter-related genetic, biochemical, cellular and tissue …
phenomenon involving many inter-related genetic, biochemical, cellular and tissue …
Targeting mast cells tryptase in tumor microenvironment: a potential antiangiogenetic strategy
M Ammendola, C Leporini, I Marech… - BioMed research …, 2014 - Wiley Online Library
Angiogenesis is a complex process finely regulated by the balance between angiogenesis
stimulators and inhibitors. As a result of proangiogenic factors overexpression, it plays a …
stimulators and inhibitors. As a result of proangiogenic factors overexpression, it plays a …
Synergy effects of copper and silicon ions on stimulation of vascularization by copper-doped calcium silicate
Copper (Cu) has been reported to be able to stimulate vascularization/angiogenesis, which
is critical for regeneration of vascularized tissue in tissue engineering. Silicate bioceramics …
is critical for regeneration of vascularized tissue in tissue engineering. Silicate bioceramics …
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach
Genome-wide association studies (GWAS) have begun to identify the common genetic
component to ischaemic stroke (IS). However, IS has considerable phenotypic …
component to ischaemic stroke (IS). However, IS has considerable phenotypic …
From plasminogen to plasmin: role of plasminogen receptors in human cancer
M Didiasova, L Wujak, M Wygrecka… - International Journal of …, 2014 - mdpi.com
Cell surface-associated proteolysis mediated by plasmin (PLA) is an essential feature of
wound healing, angiogenesis and cell invasion, processes that are dysregulated in cancer …
wound healing, angiogenesis and cell invasion, processes that are dysregulated in cancer …
Fractionation of an ECM hydrogel into structural and soluble components reveals distinctive roles in regulating macrophage behavior
Extracellular matrix (ECM) derived from mammalian tissues has been utilized to repair
damaged or missing tissue and improve healing outcomes. More recently, processing of …
damaged or missing tissue and improve healing outcomes. More recently, processing of …
Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells
CM Dowling, C Herranz Ors, PA Kiely - Bioscience reports, 2014 - portlandpress.com
Increasing our knowledge of the mechanisms regulating cell proliferation, migration and
invasion are central to understanding tumour progression and metastasis. The local tumour …
invasion are central to understanding tumour progression and metastasis. The local tumour …