Lung transplantation (LTx) is a treatment option for infants and children with untreatable and
otherwise fatal pulmonary diseases. To date, over 1,800 lung transplants have been …

Summary chILD encompasses a collection of rare, diffuse lung diseases. Timely recognition
of children with suspected ILD and initiation of appropriate diagnostic evaluations will …

Background Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis
(IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine …

Population-based, longitudinal studies spanning decades linking risk factors in childhood,
adolescence and early adulthood to incident clinical interstitial lung disease (ILD) events in …

Background Pulmonary alveolar proteinosis (PAP) is very rare in children. Only a few small
series have been published, with little information about long-term progression. The …

Advances in the physiology, biochemistry, molecular and cell biology of the pulmonary
surfactant system transformed the clinical care and outcome of preterm infants with …

The American Thoracic Society (ATS) recently published a clinical practice guideline
regarding the classification, evaluation, and management of childhood interstitial lung …

目的报告1 例肺表面活性物质蛋白C (SP-C) 基因I73T 突变相关性婴幼儿肺间质疾病的诊断过程,
复习文献, 探讨基因检测在诊断婴幼儿肺间质疾病中的作用. 方法总结, 分析本病例的临床 …

Background Rare chronic diseases of childhood are often complex and associated with
multiple health issues. Such conditions present significant demands on health services, but …

This report describes the first known case of Mucopolysaccharidosis type IIIA presenting with
respiratory symptoms and characteristic lung pathology. This case highlights under …