Interstitial lung disease

KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis

L Wollin, I Maillet, V Quesniaux, A Holweg… - Journal of Pharmacology …, 2014 - ASPET
The tyrosine kinase inhibitor nintedanib (BIBF 1120) is in clinical development for the
treatment of idiopathic pulmonary fibrosis. To explore its mode of action, nintedanib was …

Interstitial lung disease in systemic sclerosis

AU Wells - La Presse Médicale, 2014 - Elsevier
Based on international collaborative data, interstitial lung disease is now the most frequent
cause of death in systemic sclerosis (SSc), having supplanted renal crisis in that regard …

Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis

Idiopathic Pulmonary Fibrosis Clinical … - … England Journal of …, 2014 - Mass Medical Soc
Background Acetylcysteine has been suggested as a beneficial treatment for idiopathic
pulmonary fibrosis, although data from placebo-controlled studies are lacking. Methods In …

6-Minute walk distance is an independent predictor of mortality in patients with idiopathic pulmonary fibrosis

RM du Bois, C Albera, WZ Bradford… - European …, 2014 - Eur Respiratory Soc
6-min walk distance (6MWD) has recently been shown to be associated with the risk of
mortality in patients with idiopathic pulmonary fibrosis (IPF); however, the independent …

[HTML][HTML] Prognostic factors for myositis-associated interstitial lung disease

T Fujisawa, H Hozumi, M Kono, N Enomoto… - PLoS one, 2014 - journals.plos.org
Background Interstitial lung disease (ILD) is a common manifestation of polymyositis (PM),
dermatomyositis (DM), and clinically amyopathic dermatomyositis (CADM); however, little is …

[HTML][HTML] A cohort study of interstitial lung diseases in central Denmark

C Hyldgaard, O Hilberg, A Muller, E Bendstrup - Respiratory medicine, 2014 - Elsevier
Summary Introduction Interstitial lung diseases (ILDs) form a heterogeneous group of
diseases with varying degrees of inflammation and fibrosis. Epidemiological data based on …

Rheumatoid arthritis–associated interstitial lung disease: radiologic identification of usual interstitial pneumonia pattern

D Assayag, BM Elicker, TH Urbania, TV Colby… - Radiology, 2014 - pubs.rsna.org
Purpose To determine the accuracy of computed tomography (CT) in identifying the
histopathologic usual interstitial pneumonia (UIP) pattern in rheumatoid arthritis–associated …

Distinct characteristics of pleuroparenchymal fibroelastosis with usual interstitial pneumonia compared with idiopathic pulmonary fibrosis

T Oda, T Ogura, H Kitamura, E Hagiwara, T Baba… - Chest, 2014 - Elsevier
BACKGROUND Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial
pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) …

Potential risk of TNF inhibitors on the progression of interstitial lung disease in patients with rheumatoid arthritis

T Nakashita, K Ando, N Kaneko, K Takahashi… - BMJ open, 2014 - bmjopen.bmj.com
Objectives Biological therapy represents important advances in alleviating rheumatoid
arthritis (RA), but the effect on interstitial lung disease (ILD) has been controversial. The …