The biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literature
L Xiong, CK Edwards III, L Zhou - International journal of molecular …, 2014 - mdpi.com
CD147 or EMMPRIN is a member of the immunoglobulin superfamily in humans. It is widely
expressed in human tumors and plays a central role in the progression of many cancers by …
expressed in human tumors and plays a central role in the progression of many cancers by …
MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer
X Zhou, Y Hu, L Dai, Y Wang, J Zhou, WW Wang… - PLoS …, 2014 - journals.plos.org
Epidermal growth factor receptor (EGFR) overexpression and activation result in increased
proliferation and migration of solid tumors including ovarian cancer. In recent years …
proliferation and migration of solid tumors including ovarian cancer. In recent years …
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway
F Fei, X Li, L Xu, D Li, Z Zhang, X Guo, H Yang… - Annals of surgical …, 2014 - Springer
Background It has been reported that CD147 and CD98 heavy chain (CD98hc) form a
complex on the cell plasma membrane of several cancers; however, whether this complex …
complex on the cell plasma membrane of several cancers; however, whether this complex …
Doxorubicin induces drug resistance and expression of the novel CD44st via NF-κB in human breast cancer MCF-7 cells
XJ Fang, H Jiang, YQ Zhu, LY Zhang… - Oncology …, 2014 - spandidos-publications.com
CD44, a major receptor for hyaluronan (HA), is a member of a class of adhesion molecules
of unknown classification involved in cell proliferation, differentiation, migration …
of unknown classification involved in cell proliferation, differentiation, migration …
CD147 expression in human gastric cancer is associated with tumor recurrence and prognosis
D Chu, S Zhu, J Li, G Ji, W Wang, G Wu, J Zheng - PloS one, 2014 - journals.plos.org
CD147 is correlated with tumor aggressiveness in various human malignancies. Here, we
investigated CD147 protein expression in 223 patients with gastric cancer by …
investigated CD147 protein expression in 223 patients with gastric cancer by …
Expression of CD147 and Lewis y antigen in ovarian cancer and their relationship to drug resistance
J Gao, Z Hu, J Liu, D Liu, Y Wang, M Cai, D Zhang… - Medical oncology, 2014 - Springer
The purpose of this study was to investigate the relationship between the expression of
CD147 and Lewis y antigen in epithelial ovarian carcinoma tissues and resistance to …
CD147 and Lewis y antigen in epithelial ovarian carcinoma tissues and resistance to …
Upregulation of CD147 protects hepatocellular carcinoma cell from apoptosis through glycolytic switch via HIF-1 and MCT-4 under hypoxia
X Ke, Y Chen, P Wang, J Xing, Z Chen - Hepatology international, 2014 - Springer
Purpose Hypoxia is a vital factor in supporting and directing hepatocellular carcinoma
(HCC) progression. HIF-1 transactivates target genes involved in metabolic reprogramming …
(HCC) progression. HIF-1 transactivates target genes involved in metabolic reprogramming …
Advances in investigations on the mechanism of cancer multidrug resistance and the liposomes-based treatment strategy
F Zeng, RJ Ju, XT Li, WL Lu - Journal of Pharmaceutical Investigation, 2014 - Springer
Multidrug resistance is a major cause that leads to the refractory of cancers after a
combination strategy by chemotherapy, radiation and surgical treatment. Among the …
combination strategy by chemotherapy, radiation and surgical treatment. Among the …