Developed societies, although having successfully reduced the burden of infectious
disease, constitute an environment where metabolic, cardiovascular, and autoimmune …

An essential link between the kidney and blood pressure control has long been known.
Here, we review evidence supporting the premise that an impaired capacity of the kidney to …

Current teaching states that when sodium intake is increased from low to high levels, total-
body sodium (TBNa) and water increase until daily sodium excretion again equals intake …

Sodium balance is not just a renal affair : Current Opinion in Nephrology and Hypertension
Sodium balance is not just a renal affair : Current Opinion in Nephrology and Hypertension Log in …

Highlights•Genetic dissection of ENaC mediated sodium transport validate novel drug
targets.•Signaling pathways controlling ENaC activity identifies novel drug targets.• …

BACKGROUND Sodium intake is an important determinant of blood pressure; therefore,
reduction of intake may be an attractive population-based target for chronic kidney disease …

Epidemiological studies of the association of sodium and potassium intake with
cardiovascular disease risk have almost exclusively relied on self-reported dietary data …

A successful pregnancy requires an accommodating environment. Salt and water availability
are critical for plasma volume expansion. Any changes in sodium intake would alter …

Purpose The objective was to check if 520 days in confinement (MARS 500), may affect the
main peripheral arterial diameter and wall thickness and the main vein size. Method …

Background Long-term space travel simulation experiments enabled to discover different
aspects of human metabolism such as the complexity of NaCl salt balance. Detailed …