Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI?

GJ Biessels, YD Reijmer - Diabetes, 2014 - Am Diabetes Assoc
Diabetes is associated with cognitive dysfunction and an increased risk of dementia. This
article addresses findings with brain MRI that may underlie cognitive dysfunction in diabetes …

Type 2 diabetes as a risk factor for cognitive impairment: current insights

H Umegaki - Clinical interventions in aging, 2014 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a risk factor for cognitive dysfunction and dementia in the
elderly. T2DM has been thought to be associated with vascular diseases, eventually leading …

Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment

SF Abcouwer, TW Gardner - Annals of the New York Academy …, 2014 - Wiley Online Library
Diabetic retinopathy (DR) impairs vision of patients with type 1 and type 2 diabetes,
associated with vascular dysfunction and occlusion, retinal edema, hemorrhage, and …

Enhancement of vasoreactivity and cognition by intranasal insulin in type 2 diabetes

V Novak, W Milberg, Y Hao, M Munshi, P Novak… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE To determine acute effects of intranasal insulin on regional cerebral perfusion
and cognition in older adults with type 2 diabetes mellitus (DM). RESEARCH DESIGN AND …

Alzheimer's disease and type 2 diabetes: multiple mechanisms contribute to interactions

A Jayaraman, CJ Pike - Current diabetes reports, 2014 - Springer
Obesity, metabolic syndrome, and type 2 diabetes (T2D) are related disorders with
widespread deleterious effects throughout the body. One important target of damage is the …

Diabetes, markers of brain pathology and cognitive function: the Age, Gene/Environment Susceptibility–Reykjavik Study

C Qiu, S Sigurdsson, Q Zhang, MK Jonsdottir… - Annals of …, 2014 - Wiley Online Library
Objective We investigated whether, and the extent to which, vascular and degenerative
lesions in the brain mediate the association of diabetes with poor cognitive performance …

Brain imaging in type 2 diabetes

M Brundel, LJ Kappelle, GJ Biessels - European …, 2014 - Elsevier
Type 2 diabetes mellitus (T2DM) is associated with cognitive dysfunction and dementia.
Brain imaging may provide important clues about underlying processes. This review focuses …

[HTML][HTML] Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone …

E Tchistiakova, ND Anderson, CE Greenwood… - NeuroImage: Clinical, 2014 - Elsevier
Objective Type 2 diabetes mellitus is characterized by metabolic dysregulation in the form of
hyperglycemia and insulin resistance and can have a profound impact on brain structure …

Gray matter volume abnormalities in type 2 diabetes mellitus with and without mild cognitive impairment

Y Zhang, X Zhang, J Zhang, C Liu, Q Yuan, X Yin… - Neuroscience …, 2014 - Elsevier
This study sought to evaluate the potential brain gray matter (GM) volume changes that
occur with the transition from normal cognition to mild cognitive impairment (MCI) in patients …

[HTML][HTML] A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the …

AHM Kilgour, OM Todd, JM Starr - BMC geriatrics, 2014 - Springer
Background An association between cognition and physical function has been shown to
exist but the roles of muscle and brain structure in this relationship are not fully understood …