The relationship between osteoarthritis and osteoporosis

GI Im, MK Kim - Journal of bone and mineral metabolism, 2014 - Springer
The relationship between osteoarthritis (OA) and osteoporosis (OP), the two most common
skeletal disorders related to aging, is controversial. Previous studies suggest that OA is …

Selection bias in rheumatic disease research

HK Choi, US Nguyen, J Niu, G Danaei… - Nature reviews …, 2014 - nature.com
The identification of modifiable risk factors for the development of rheumatic conditions and
their sequelae is crucial for reducing the substantial worldwide burden of these diseases …

Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints

D Prieto-Alhambra, A Judge, MK Javaid… - Annals of the …, 2014 - ard.bmj.com
Objectives Data on the incidence of symptomatic osteoarthritis (OA) are scarce. We
estimated incidence of clinical hip, knee and hand OA, and studied the effect of prevalent OA …

Effects of obesity on lower extremity muscle function during walking at two speeds

ZF Lerner, WJ Board, RC Browning - Gait & posture, 2014 - Elsevier
Walking is a recommended form of physical activity for obese adults, yet the effects of
obesity and walking speed on the biomechanics of walking are not well understood. The …

Body mass index and knee osteoarthritis risk: a dose‐response meta‐analysis

ZY Zhou, YK Liu, HL Chen, F Liu - Obesity, 2014 - Wiley Online Library
Objective Evidence shows obesity is an important risk factor for knee osteoarthritis (OA).
However, the dose‐response relationship between body mass index (BMI) and knee OA risk …

Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin‐1

O Alvarez‐Garcia, NH Rogers, RG Smith… - Arthritis & …, 2014 - Wiley Online Library
Objective Obesity is a major risk factor for the development of osteoarthritis (OA) that is
associated with a state of low‐grade inflammation and increased circulating levels of …

Risk factors for knee replacement due to primary osteoarthritis, a population based, prospective cohort study of 315,495 individuals

H Apold, HE Meyer, L Nordsletten, O Furnes… - BMC musculoskeletal …, 2014 - Springer
Background Osteoarthritis (OA) of the knee is a common and disabling condition. We
wanted to investigate the modifiable risk factors Body Mass Index (BMI) and physical activity …

The effects of walking speed on tibiofemoral loading estimated via musculoskeletal modeling

ZF Lerner, DJ Haight, MS DeMers… - Journal of applied …, 2014 - journals.humankinetics.com
Net muscle moments (NMMs) have been used as proxy measures of joint loading, but
musculoskeletal models can estimate contact forces within joints. The purpose of this study …

Meeting physical activity guidelines and the risk of incident knee osteoarthritis: A population‐based prospective cohort study

KE Barbour, JM Hootman, CG Helmick… - Arthritis care & …, 2014 - Wiley Online Library
Objective Knee osteoarthritis (OA) is a leading cause of disability and joint pain. Although
other risk factors of knee OA have been identified, how physical activity affects incident knee …

Relationship between physical activity and chronic musculoskeletal pain among community-dwelling Japanese adults

M Kamada, J Kitayuguchi, IM Lee, T Hamano… - Journal of …, 2014 - jstage.jst.go.jp
Background: Both little and excessive physical activity (PA) may relate to chronic
musculoskeletal pain. The primary objective of this study was to characterize the relationship …